Mortality, energy reserves, and oxidative stress responses of three native freshwater mussels to temperature as an indicator of potential impacts of climate change: A laboratory experimental approach

Said, Radwa Mohamed; Nassar, Safaa Ezzat

doi:10.1016/j.jtherbio.2021.103154

Cited by 20 publications

(4 citation statements)

References 70 publications

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“…In recent years, extreme weather conditions, especially high temperatures, threatening the survival of nearly all marine organisms have occurred frequently around the world [ 1 , 2 ]. Several researchers have suggested that heat stress adversely affects all aquatic organisms through various mechanisms, including the disturbance of energy metabolism, mitochondrial disorders and oxidative stress [ 3 , 4 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Metabonomic Analysis Provides New Insights into the Response of Zhikong Scallop (Chlamys farreri) to Heat Stress by Improving Energy Metabolism and Antioxidant Capacity

et al. 2022

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Temperature is an important factor affecting the growth, development and survival of marine organisms. A short episode of high temperature has been proven to be a severe threat to sustainable shellfish culture. Zhikong scallop (Chlamys farreri), a shellfish with broad economic and biological value in North China, has frequently experienced heat stress in summer in recent years. To understand the effects of heat stress on shellfish, the metabolism of C. farreri was analyzed after exposure to 27 °C for either 6 h or 30 d. After 6 h of heat stress exposure, a total of 326 and 264 significantly different metabolites (SDMs) were identified in gill and mantle tissues, respectively. After 30 d of heat stress exposure, a total of 381 and 341 SDMs were found in the gill and mantle tissues, respectively. These SDMs were mainly related to the metabolism of amino acids, carbohydrates, lipids and nucleotides. A decline in pyruvic acid, and an increase in citric acid and fumaric acid in the gills and mantle of C. farreri indicated an alteration in energy metabolism, which may be attributed to increased ATP production in order to overcome the heat stress. Among the SDMs, 33 metabolites, including pyruvic acid, glycine and citric acid, were selected as potential biomarkers for heat stress response in C. farreri. In addition, a decline in glutamine and β-Alanine levels indicated oxidative stress in C. farreri exposed to heat, as well as an increase in the total antioxidant capacity (T-AOC). Our findings suggested C. farreri have the potential to adapt to heat stress by regulating energy metabolism and antioxidant capacity.

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Section: Introductionmentioning

confidence: 99%

Metabonomic Analysis Provides New Insights into the Response of Zhikong Scallop (Chlamys farreri) to Heat Stress by Improving Energy Metabolism and Antioxidant Capacity

et al. 2022

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“…The normal life activities of mussels are vulnerable to external environmental stressors, including hypoxia, sea warming, and acidification [28][29][30]. Exposure to high-temperature conditions significantly downregulates the organism's energy reserves and weakens its immune function [31,32]. As the molecular response mechanism related to injury and death in mussels after high-temperature stress remains unclear, we examined the responses of M. coruscus to high-temperature exposure to investigate the molecular and cellular mechanisms involved.…”

Section: Discussionmentioning

confidence: 99%

Insights into the Response in Digestive Gland of Mytilus coruscus under Heat Stress Using TMT-Based Proteomics

Wang

Lin

et al. 2023

Animals

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Ocean warming can cause injury and death in mussels and is believed to be one of the main reasons for extensive die-offs of mussel populations worldwide. However, the biological processes by which mussels respond to heat stress are still unclear. In this study, we conducted an analysis of enzyme activity and TMT-labelled based proteomic in the digestive gland tissue of Mytilus coruscus after exposure to high temperatures. Our results showed that the activities of superoxide dismutase, acid phosphatase, lactate dehydrogenase, and cellular content of lysozyme were significantly changed in response to heat stress. Furthermore, many differentially expressed proteins involved in nutrient digestion and absorption, p53, MAPK, apoptosis, and energy metabolism were activated post-heat stress. These results suggest that M. coruscus can respond to heat stress through the antioxidant system, the immune system, and anaerobic respiration. Additionally, M. coruscus may use fat, leucine, and isoleucine to meet energy requirements under high temperature stress via the TCA cycle pathway. These findings provide a useful reference for further exploration of the response mechanism to heat stress in marine mollusks.

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“…Climate change can impact the natural flow and thermal regimes of a river, which in turn can affect mussel survival (Luck and Ackerman 2022;Said and Nassar 2022). Forecast modeling predicts changes in temperature and flow associated with precipitation, runoff, groundwater, and evapotranspiration; areas predicted to have adverse climate-induced changes to mussel habitat may not be good stocking locations.…”

Section: Do Climate Forecasts Negatively Impact Mussel Habitat?mentioning

confidence: 99%

Watershed selection to support freshwater mussel restoration: an open-loop decision guide

J.¹,

David

et al. 2023

Cooperator Science Series

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Mortality, energy reserves, and oxidative stress responses of three native freshwater mussels to temperature as an indicator of potential impacts of climate change: A laboratory experimental approach

Cited by 20 publications

References 70 publications

Metabonomic Analysis Provides New Insights into the Response of Zhikong Scallop (Chlamys farreri) to Heat Stress by Improving Energy Metabolism and Antioxidant Capacity

Metabonomic Analysis Provides New Insights into the Response of Zhikong Scallop (Chlamys farreri) to Heat Stress by Improving Energy Metabolism and Antioxidant Capacity

Insights into the Response in Digestive Gland of Mytilus coruscus under Heat Stress Using TMT-Based Proteomics

Watershed selection to support freshwater mussel restoration: an open-loop decision guide

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