Mortality in acute stroke: predictive value of lipid profile and routine investigations

Abstract

Acute stroke is a medical emergency which can cause permanent neurological damage, complications and even may leads to death. Results of stroke vary widely depending on the size and location of the lesions. It is a heterogeneous condition with respect to prognosis. It is not possible to predict exact outcome of stroke with accuracy. The chances of survival in stroke depend on a great variety of variables. Globally, approximately 15 million new acute stroke events occur every year and approximately 55 million people had stroke at some time in the past. Two thirds of these individuals live in lowand middle-income countries such as India. By 2050, it is anticipated that 80% of stroke events will occur in people living in these regions. 1 A recent Indian study have shown different prevalence rates in rural and urban areas (rural areas 84-262/100,000; urban areas 334-424/100,000) with incidence rate of 119-145/100,000 and 30 day case fatality was found to be 41.08%. 2 According to Indian collaborative acute stroke study (2002)(2003)(2004) with 2162 cases, stroke incidence higher in age group of 41-70

The role of radiologic, clinical and biochemical parameters in prediction of stroke mortality

“…The ESR, LDL, and total cholesterol have been previously reported to significantly predict mortality; however, this study found insignificant results with these parameters. 14 This study has certain limitations. Firstly, the low number of patients in the sample may explain why significant results related to CRP values were not obtained, unlike in the reviewed literature.…”

“…4 As revealed in the literature review, stroke volume, NIHSS score, and CRP are among the prognostic parameters that have been previously described. Furthermore, the neutrophil/lymphocyte ratio and the routine blood parameters of blood urea, creatinine, and glucose, [11][12][13][14] have previously been proven as prognostic markers although they were not evaluated in the current study. Other significant prognostic factors, such as advanced age, dementia, and several chronic comorbidities including heart failure, ischemic heart disease, and atrial fibrillation [15][16][17][18] have been reported.…”

Kadar Fibrinogen Sebagai Faktor Prognostik Pasien Perdarahan Intraserebral Spontan

“…Chaurisa menyatakan bahwa GCS awal yang buruk adalah prediktor peningkatan mortalitas, 11 demikian pula Pandey menyatakan bahwa skor GCS yang rendah merupakan prediktor kuat mortalitas. 12 Didapatkan pada penelitian ini, bahwa skor GCS preoperasi memiliki kecenderungan untuk dapat dijadikan sebagai faktor prediksi prognostik pada pasien perdarahan intra serebral spontan yang menjalani operasi.…”