Frailty is a multifactorial geriatric syndrome. The age-related cumulative decline across interrelated physiological systems and impaired homeostatic reserves results in the increased vulnerability to stressors, especially exposed to acute or chronic illness. 1,2 Accordingly, older adults with frailty are related to an increment risk for the adverse health outcomes, including falls, 1 institutionalization, 3 delirium, 4 disability, 5 and mortality. 6 It was estimated that the prevalence rate of frailty was 19.6% in China. 7 With advancing age, frailty progresses at a great rate, which poses a grave threat to public health.