Motor and Sensory Function of the Rectum in Different Subtypes of Constipation

Penning, Corine; Steens, Jeroen; Schaar, Peter; Kuyvenhoven, J.; Delemarre, J. B. V. M.; Lamers, C. B. H. W.; Masclee, Ad

doi:10.1080/00365520150218039

Cited by 33 publications

(33 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, data on the prevalence of specific dyspeptic symptoms among constipated patients are uncertain [3]. …”

Section: Discussionmentioning

confidence: 99%

“…It has been hypothesized that constipation is part of a generalized gastrointestinal (GI) motor disorder in which proximal GI motility can also be impaired [1,2,3,4]. Indeed, alterations in small bowel motility, gastric emptying and gallbladder contraction have been reported in chronically constipated patients [1,2,3,4,5,6].…”

Section: Introductionmentioning

confidence: 99%

“…Indeed, alterations in small bowel motility, gastric emptying and gallbladder contraction have been reported in chronically constipated patients [1,2,3,4,5,6]. …”

Section: Introductionmentioning

confidence: 99%

“…Penning et al [1, 3] have shown that in the subgroup of patients with slow transit chronic constipation, the reduced colonic motility may be responsible for dyspeptic symptoms, probably by influencing gastric emptying rate, or gallbladder responses. But, again, whether such changes in motor functions translate into different dyspeptic symptoms is uncertain.…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, Talley et al [9] have reported an increased prevalence of early satiety and bloating symptoms in the subset of patients with constipation-prevalent IBS. However, lower and upper abdominal symptoms also overlapped in some constipated patients who did not fulfill the criteria for IBS, but data on the prevalence of specific dyspeptic symptoms in these patients are uncertain [3]. …”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Symptoms and Pathophysiological Correlations in Patients with Constipation and Functional Dyspepsia

et al. 2005

View full text Add to dashboard Cite

Introduction: Patients with constipation often report dyspeptic symptoms, but whether constipation is associated with specific dyspeptic symptoms and altered gastrointestinal (GI) motility, remains to be established. Our aim was to study symptoms association and GI motility parameters in patients with constipation and functional dyspepsia. Patients and Method: 42 patients with different symptoms and severity of constipation and dyspepsia were enrolled. Scintigraphic gastric emptying, colonic transit time and gallbladder contraction were studied in all subjects. Results: No significant association was observed between individual symptoms of constipation and dyspepsia. Patients with more severe constipation did not have higher dyspepsia severity scores. Colonic transit time, gastric half emptying and gallbladder contraction were not significantly correlated. Although patients with severe nausea had faster colonic transit than those with absent/mild symptom (19 ± 2 vs. 48 ± 7 h; p < 0.05), the multivariate analysis only revealed a significant association between severe postprandial fullness, delayed t_1/2 (OR 1.05, CI 1–1.1) and impaired gallbladder contraction (OR 0.94, CI 0.89–0.99). Conclusions: Constipation was not associated with severity, or any particular dyspeptic symptom. Although motor abnormalities of both colon and proximal GI tract regions existed in the subset of constipated dyspeptic patients, they did not seem associated with the genesis of different dyspeptic symptoms.

show abstract

“…However, data on the prevalence of specific dyspeptic symptoms among constipated patients are uncertain [3]. …”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Indeed, alterations in small bowel motility, gastric emptying and gallbladder contraction have been reported in chronically constipated patients [1,2,3,4,5,6]. …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations