Movement Disorders in Patients With Multiple Sclerosis

Ахмедова, Г М; Сабиров, Ж Ф; YAKUPOV, M. A.; Хайбуллин, Т И

doi:10.17513/spno.28058

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…MS has a wide range of clinical manifestations [14,15]. Fatigue is one of the leading syndromes observed in this category of patients and which has two components in its structure -motor and non-motor [16,17].…”

Section: Introductionmentioning

confidence: 99%

Rationale for the efficiency of transcranial magnetic stimulation in multiple sclerosis

Gaponov

2021

Eureka: HS

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The aim. Based on the analysis and comprehensive clinical and neurological evaluation of the results to substantiate the effectiveness of transcranial magnetic stimulation (TMS) in the treatment and rehabilitation of patients with multiple sclerosis (MS). Methods. A total of 110 MS patients were included in the study. The control group consisted of 30 patients who received pathogenetic therapy and 80 patients who underwent a course of rhythmic transcranial magnetic stimulation (rTMS) together with pathogenetic therapy. Results. The results obtained during the study indicate the complex multifactorial nature of fatigue and its significant impact on the clinical manifestations of MS. Also, the use of rTMS reduced the severity of the main neurological symptoms of MS. The improvement in the overall EDSS scale in the group of patients receiving rTMS was statistically significant: from 5.0±1.9 points to 4.5±2.0 points (p<0.01), in the comparison group (p>0.05). Under the influence of TMS, gait function improved, but these indicators were statistically insignificant (p>0.05). The greatest effect of rTMS was obtained on the manifestations of fatigue and also extended to its cognitive and psychosocial components. The obtained patterns are confirmed in the analysis of indicators on the SCA and FS scales. Involvement in the treatment of patients with MS rTMS allowed to achieve a significant reduction in the manifestations of all components of fatigue: from 76.0±20.9 points to 75.5±20.5 points (p<0.05). The data obtained during the study confirm the effectiveness, safety and viability of non-invasive neuromodulation by rTMS in the treatment and rehabilitation of patients with MS. Conclusions. The use of rTMS has a positive effect on the manifestations of fatigue, both motor and cognitive, in patients with MS at all types of course and at different stages of progression. Non-invasiveness, safety and ease of use, the possibility of differentiated use allow the use of rTMS in the clinic of rehabilitation treatment and become an important component of active drug and non-drug rehabilitation of patients with MS.

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Section: Introductionmentioning

confidence: 99%

Rationale for the efficiency of transcranial magnetic stimulation in multiple sclerosis

Gaponov

2021

Eureka: HS

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Physical rehabilitation and recovery in neurological diseases

Livak¹,

Korchuk²,

Kozhukh³

2022

Shidnoevr. z. vnutr. simejnoi med.

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The author proved that the problem of neurological diseases is relevant despite the high development of medicine, because in conditions of stress, constant fatigue and poor ecology, we see the growth of patients with nervous disorders. Every year, more and more people of all ages turn to doctors with symptoms that indicate complex neurological diseases. Neurology includes a large number of diseases that can occur after viral diseases or due to improper lifestyle. The most common neurological diseases that cause a large number of deaths in Ukraine are Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. Some neurological diseases are more treatable and easier to tolerate, the progression and development of which can be stopped, while others are severe, which official medicine defines as incurable and lead to disability. It is important to seek the help of a specialist in time to correctly diagnose the disease and avoid unforeseen complications. For each patient it is necessary to select an individual treatment program that depends on the severity of the disease and diagnosis. Today, such a complex and currently incurable neurological disease as multiple sclerosis is becoming more common. This is a chronic autoimmune disease in which the myelin sheath of the nerve fibers of the brain and spinal cord is damaged and thus the functioning of the nervous system is disrupted. Today, this disease is one of the leading causes of disability in young patients. Occurs for unknown reasons and is constantly progressing, leading to serious physical changes and disability. The author argues that physical rehabilitation is a natural and extremely effective method of treating neurological diseases, including multiple sclerosis.

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Movement Disorders in Patients With Multiple Sclerosis

Cited by 2 publications

References 7 publications

Rationale for the efficiency of transcranial magnetic stimulation in multiple sclerosis

Rationale for the efficiency of transcranial magnetic stimulation in multiple sclerosis

Physical rehabilitation and recovery in neurological diseases

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