It is known that the so-called rotation minimizing (RM) frames allow for a simple and elegant characterization of geodesic spherical curves in Euclidean, hyperbolic, and spherical spaces through a certain linear equation involving the coefficients that dictate the RM frame motion [L.C.B. da Silva and J.D. da Silva, Mediterr. J. Math. 15, 70 (2018)]. Here, we shall prove the converse, i.e., we show that if all geodesic spherical curves on a Riemannian manifold are characterized by a certain linear equation, then all the geodesic spheres with a sufficiently small radius are totally umbilical and, consequently, the given manifold has constant sectional curvature. We also furnish two other characterizations in terms of (i) an inequality involving the mean curvature of a geodesic sphere and the curvature function of their curves and (ii) the vanishing of the total torsion of closed spherical curves in the case of threedimensional manifolds. Finally, we also show that the same results are valid for semi-Riemannian manifolds of constant sectional curvature.Keywords Rotation minimizing frame · totally umbilical submanifold · geodesic sphere · spherical curve · space form Mathematics Subject Classification (2010) 53A04 · 53A05 · 53B20 · 53C21 This is a pre-print of an article published in Annali di Matematica Pura ed Applicata. The final authenticated version is available online at https://doi.