Abstract:Moyamoya disease is a chronic occlusion of a major vessel of the circle of Willis leading to opening of cerebral collaterals. Moyamoya is common in Japan, but cases from Europe and America were reported 1. Its etiology could be idiopathic (primary Moyamoya), secondary (inherited), hematological and post infections 2. It has a special characteristic appearance in the angiography described as "puff of smoke" 3 .
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