MR Imaging Findings in Patients with Secondary Intracranial Hypertension

Rohr, Axel; Riedel, Christian; Fruehauf, M.-C.; Baalen, Andreas van; Bartsch, Thorsten; Hedderich, J.; Alfke, K.; Doerner, Lutz; Jansen, Olav

doi:10.3174/ajnr.a2463

Cited by 57 publications

(56 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Due to the invasive nature of testing CSFP, noninvasive measures are desirable. Other techniques that have been explored include IOP measurement, 19 optic nerve sheath width measurement by ultrasonography 20 or MRI, 21,22 and an approach using transcranial Doppler technology. 23 Unfortunately, limitations exist for each of these techniques as well as the technical approach that is being used to estimate CSFP.…”

Section: Discussionmentioning

confidence: 99%

Analysis of Cerebrospinal Fluid Pressure Estimation Using Formulae Derived From Clinical Data

Fleischman

Bicket

Stinnett

et al. 2016

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

PURPOSE. To evaluate a frequently used regression model and a new, modified regression model to estimate cerebrospinal fluid pressure (CSFP). METHODS. Datasets from the Beijing iCOP study from Tongren Hospital, Beijing, China, and the Mayo Clinic, Rochester, Minnesota, were tested in this retrospective, case-control study. An often-used regression model derived from the Beijing iCOP dataset, but without radiographic data, was used to predict CSFP by using demographic and physiologic data. A regression model was created using the Mayo Clinic dataset and tested against a validation group. The Mayo Clinic-derived formula was also tested against the Beijing Eye Study population. Intraclass correlation was used to assess predicted versus actual CSFP. RESULTS. The Beijing-derived regression equation was reported to have an intraclass correlation coefficient (ICC) of 0.71, indicating strong correlation between predicted and actual CSFP in the study population. The Beijing iCOP regression model poorly predicted CSFP in the Mayo Clinic population with an ICC of 0.14. The Mayo Clinic-derived regression model similarly did not predict CSFP in its Mayo Clinic validation group (ICC 0.28 6 0.04) nor in the Beijing Eye Study population (ICC 0.06). CONCLUSIONS. Formulae used to predict CSFP derived from clinical data fared poorly against a large retrospective dataset. This may be related to differences in lumbar puncture technique, in the populations tested, or the timing of collection of physiologic variables in the Mayo Clinic dataset. Caution should be used when interpreting results based on formulaic derivation of CSFP.

show abstract

Section: Discussionmentioning

confidence: 99%

Analysis of Cerebrospinal Fluid Pressure Estimation Using Formulae Derived From Clinical Data

Fleischman

Bicket

Stinnett

et al. 2016

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

show abstract

“…The variability associated with subjective rating may partly explain reported differences in frequency of these findings in IIH and secondary IH. 3,4 Automated quantitation of the globe distortion may help to overcome the limitations associated with the subjective assessment and thereby improve diagnostic accuracy. The significant association between the subjective rating and the computer-derived GF measure supports the feasibility for a reliable automated quantitation of globe flatness.…”

Section: Discussionmentioning

confidence: 99%

“…Work by Agid et al 3 assessing several cross-sectional neuroimaging signs seen in IIH suggests that posterior globe flattening has the strongest diagnostic value, with specificity of 100%, whereas optic nerve protrusion was not significantly associated with IIH. In contrast, Rohr et al 4 assessed similar signs in patients with secondary IH and reported specificity of 78% for globe flattening and 100% for optic disc protrusion. Both studies, however, used subjective visual inspection to determine the presence of flattening and optic nerve protrusion.…”

mentioning

confidence: 98%

“…[1][2][3][4][5] These findings have been reported primarily in idiopathic intracranial hypertension (IIH) [1][2][3] but also in secondary IH, including sinus thrombosis and nonthrombotic cases of venous sinus occlusions. 4 Posterior sclera flattening has also been observed in astronauts after long-duration exposure to microgravity. 5,6 Occurrence rates of globe flattening and optic nerve protrusion in IIH and secondary IH are reported to be different.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Automated Quantitation of the Posterior Scleral Flattening and Optic Nerve Protrusion by MRI in Idiopathic Intracranial Hypertension

Alperin¹,

Bagci²,

Lam

et al. 2013

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

show abstract

“…A widespread involvement of the venous sinuses was associated with very high CSF pressure. They hypothesized that IH compresses the dural sleeve of the venous sinuses 38 . Regardless of cause or effect, patients with IIH are likely to have raised venous pressures and stenotic lesions in their lateral venous sinuses.…”

Section: Cross Sectional Mri/ Ct Findings In Iihmentioning

confidence: 99%

Idiopathic Intracranial Hypertension: Diagnostic Accuracy of the Transverse Dural Venous Sinus Attenuation on CT Scans

et al. 2014

View full text Add to dashboard Cite

SUMMARY -Idiopathic intracranial hypertension (IIH) is a clinical disorder of unknown etiology. It may exhibit several non-specific imaging findings. We observed that patients with intracranial hypertension demonstrate intracranial venous sinus attenuation with changes in the contour and caliber of the distal transverse sinus. This can be seen on routine non-contrast sagittal reformatted CT images of the brain. We have termed this the venous attenuation sign (VAS). This study evaluated the VAS as a marker for IIH assessing the transverse sinuses on sagittal reformatted non-contrast CT for the presence of a VAS in 25 patients with IIH and 24 control patients. Scans were independently assessed in a blinded fashion by three readers. The readers identified the VAS

show abstract

MR Imaging Findings in Patients with Secondary Intracranial Hypertension

Abstract: BACKGROUND AND PURPOSE: IH can alter the configuration of anatomic structures of the central nervous system. We determined the sensitivity and specificity of MR imaging to detect these changes in patients with secondary IH.

Cited by 57 publications

References 31 publications

Analysis of Cerebrospinal Fluid Pressure Estimation Using Formulae Derived From Clinical Data

Analysis of Cerebrospinal Fluid Pressure Estimation Using Formulae Derived From Clinical Data

Automated Quantitation of the Posterior Scleral Flattening and Optic Nerve Protrusion by MRI in Idiopathic Intracranial Hypertension

Idiopathic Intracranial Hypertension: Diagnostic Accuracy of the Transverse Dural Venous Sinus Attenuation on CT Scans

Contact Info

Product

Resources

About