MR imaging of a malignant schwannoma and an osteoblastoma with fluid-fluid levels. Report of two new cases

Vilanova, Joan C.; Dolz, J. L.; Leon, Julio; Aparicio, A.; Aldomà, Jordi; Capdevila, Antoni

doi:10.1007/s003300050552

Cited by 29 publications

(14 citation statements)

References 14 publications

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“…Benign lesions that demonstrate FFLs include chondroblastoma [10][11][12][13][14], giant cell tumour (GCT) [14][15][16][17][18], cystic fibrous dysplasia [1,14,[19][20][21][22], simple bone cyst (SBC) [1,4,14,23,24], intraosseous ganglion [25], osteomyelitis [5,14], osteoblastoma [26,27], Langerhans' cell histiocytosis (LCH) [28,29], ossifying fibroma [30], intraosseous lipoma [14], enchondroma [14], brown tumour [31,32] and fibroxanthoma [21,33]. Malignant tumours that demonstrate FFLs include telangiectatic osteosarcoma [3,6,14,34,35], conventional osteosarcoma [1,14], osteosarcoma post-chemotherapy [6], malignant fibrous histocytoma (MFH)/fibrosarcoma [1,14,36], plasmacytoma [37], meta...…”

Section: Introductionmentioning

confidence: 99%

Fluid-fluid levels in bone neoplasms: variation of T1-weighted signal intensity of the superior to inferior layers—diagnostic significance on magnetic resonance imaging

Alyas

Saifuddin

2008

Eur Radiol

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The diagnostic relevance of the relative T1-weighted (T1W) and T2-weighted (T2W)/short tau inversion recovery (STIR) MRI signal intensity characteristics of the superior to inferior fluid layers within fluid-fluid levels (FFLs) found in bone tumours was investigated. A retrospective analysis was performed of MRI studies of 2,568 patients presenting with a suspected bone tumour over an 8-year period. Final diagnosis was made by biopsy/surgical resection or characteristic imaging/clinical findings. Subjects were divided by the absence/presence of FFLs and benign/malignant histology. Cases with FFLs were sub-categorised by the relative signal intensity of the superior/inferior layer as high/low or low/high on T1W and T2W/STIR sequences. Out of the total of 2,568 cases, 214 (8.3%, CI 7.3-9.5%) had FFLs and 2,354 (91.7%, CI 90.5-92.7%) had no FFLs. All 214 cases with FFLs had T2W/STIR sequences available, all demonstrating high/low signal intensity characteristics; 135/214 (63.1%, CI 56.2-69.6%) were benign and 79/214 (36.9%, CI 30.4-43.8%) were malignant. Out of the 214 patients, 151 had T1W sequences performed; 52 showed high/low signal intensity, of which 30 (57.7%, CI 34.2-71.3%) were benign and 22 (42.3%, CI 28.7-56.8%) were malignant (P = 0.06 compared with no FFL group); 50 showed low/high signal intensity, of which 40 (80%, CI 66.3-90.0%) were benign and ten (20%, CI 10.0-33.7%) were malignant (P = 0.0000, compared with the no FFL group). The low/high and high/low groups had a significantly greater proportion of benign and malignant lesions, respectively (P = 0.015). In conclusion, all FFLs showed high/low signal intensity characteristics on T2W/STIR sequences. Low/high signal on T1W was significantly associated with benign disease. Malignancy may occur slightly more frequently with high/low signal on T1W.

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Section: Introductionmentioning

confidence: 99%

Fluid-fluid levels in bone neoplasms: variation of T1-weighted signal intensity of the superior to inferior layers—diagnostic significance on magnetic resonance imaging

Alyas

Saifuddin

2008

Eur Radiol

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“…It involved the suboccipital bone extending from the torcula till the foramen magnum region without the involvement of occipital condyles and the atlas. MRI characteristics show low and intermediate signal intensity on T 1 -weighted images, and low or high signal intensity on T 2 -weighted images [12,13,14]. The altered intensity seen on MRI denotes either reactive bone formation or inflammation which requires histological evidence.…”

Section: Discussionmentioning

confidence: 99%

“…Multiple burrholes within the lesion as well as in the surrounding normal bone are the key. Although osteoblastoma is a benign tumor and has a regressive tendency, it can also exhibit a potentially aggressive behavior [4,14,16,17,18]. Incomplete resection of the tumor results in local recurrence [4].…”

Section: Discussionmentioning

confidence: 99%

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Massive Benign Osteoblastoma of the Suboccipital Bone and Foramen Magnum Region

Muzumdar¹,

Balasubramaniam²,

Jhawar³

et al. 2010

Pediatr Neurosurg

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Benign osteoblastoma is an uncommon primary bone tumor frequently found in the vertebral column and long tubular bones, and rarely occurring in the calvarium. A case of a massive benign osteoblastoma of the suboccipital bone and foramen magnum region in a 9-year-old boy is reported. He presented with progressively worsening nuchal pain and headaches secondary to a bony lesion in the suboccipital and foramen magnum region. Computed tomography (CT) of the brain showed a large midline occipital/suboccipital bony lesion extending to either side (R > L) and extending from the torcula till the foramen magnum region, causing moderate obstructive hydrocephalus. The atlas was uninvolved by the tumor. In addition, the cerebellum was pushed anteriorly squashing the fourth ventricle. The tumor was completely resected with wide margins via a suboccipital route. At follow-up after 7 years, the patient was asymptomatic, and CT imaging demonstrated no recurrence. The occurrence of benign osteoblastoma in the suboccipital bone and foramen magnum region has not been reported earlier in the pediatric population. Surgical extirpation of the lesion with wide margins is advocated and can produce an excellent long-term outcome. Serial vigilant follow-up along with sequential imaging is advocated even in cases with complete resection to detect early recurrence and possible malignant transformation.

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“…In the long bones, the lesion tends to be eccentric, creating a saccular protrusion with multiple fine septae internally and sharply demarcated, bulging, scalloped borders. On CT and MRI several fluid levels (fluid-fluid) can be seen within the multicystic lesion [14,15].These are probably due to settling of degraded blood.…”

Section: Case Reportmentioning

confidence: 99%

Large Predominantly Solid Variant of Aneurysmal Bone Cyst in the Diaphysis of Femur: A Rare Entity

Rohilla¹,

Mahajan²,

Sharma³

et al. 2016

Med-Science

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Aneurysmal Bone Cyst (ABC) is a non neoplastic solitary lesion which commonly affects long tubular bones and spine. Most lesions are predominantly cystic, and affect the metaphyseal region in the long bones with extension into the diaphysis but purely diaphyseal lesions are uncommon. In this case report, we describe X-ray and magnetic resonance imaging (MRI)findings in a pathologically proved case of predominantly solid variant of ABC involving the diaphysis of femur.

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MR imaging of a malignant schwannoma and an osteoblastoma with fluid-fluid levels. Report of two new cases

Cited by 29 publications

References 14 publications

Fluid-fluid levels in bone neoplasms: variation of T1-weighted signal intensity of the superior to inferior layers—diagnostic significance on magnetic resonance imaging

Fluid-fluid levels in bone neoplasms: variation of T1-weighted signal intensity of the superior to inferior layers—diagnostic significance on magnetic resonance imaging

Massive Benign Osteoblastoma of the Suboccipital Bone and Foramen Magnum Region

Large Predominantly Solid Variant of Aneurysmal Bone Cyst in the Diaphysis of Femur: A Rare Entity

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