MR imaging of synovial sarcoma.

Morton, Marilyn J.; Berquist, T H; McLeod, Richard A.; Unni, K. Krishnan; Fh, Sim

doi:10.2214/ajr.156.2.1846054

Cited by 124 publications

(59 citation statements)

References 3 publications

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“…This is in agreement with previous studies. [4][5][6][7] The tumors were usually well-cireumscribed but focally they could be slightly diffuse. Three SS demonstrated a general diffuse appearance which is not the usual characteristic of this tumor ( Figure 3) and has, to the best of our knowledge, not been described before.…”

Section: Discussionmentioning

confidence: 99%

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Magnetic Resonance Imaging of Synovial Sarcoma

et al. 1995

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Section: Discussionmentioning

confidence: 99%

“…1 Magnetic resonance imaging is a valuable imaging method in the radiologic evaluation of musculoskeletal soft tissue tumors including synovial sarcomas. [4][5][6][7][8] We retrospectively analyzed the morphologic MRI appearance in 10 cases of histologically proven synovial sarcomas, some of these exhibiting unusual MRI findings.…”

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confidence: 99%

Magnetic Resonance Imaging of Synovial Sarcoma

et al. 1995

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“…3.16a, b ). Others have described a heterogeneous, multiloculated appearance with various degrees of internal septations, with or without fl uid-fl uid levels probably due to internal hemorrhage [ 222 ]. After administration of contrast material there is usually prompt and heterogeneous enhancement, which may demonstrate nodularity within a cystic lesion (Fig.…”

Section: Imaging Featuresmentioning

confidence: 98%

Soft Tissue Sarcomas

Parham

Kaste

Raju

et al. 2014

Pediatric Malignancies: Pathology and Imaging

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“…Although there have been several publications illustrating successful excisional biopsy of intra-articular masses arthroscopically, the consensus of musculoskeletal oncologists is that arthroscopy is not indicated as a planned primary method of biopsy for an intra-articular soft tissue mass [42][43][44][45][46]. Insufflation of the knee with saline risks intra-articular spread of tumor cells and potential extravasation into the surrounding tissues [11,22].…”

Section: Staging Treatment and Follow-upmentioning

confidence: 99%

“…However, after follow-up MRI with gradient echo and post-contrast images, most likely diagnosis was focal PVNS, or less likely, partially calcified synovial chondromatosis. One month later, the patient underwent The radiographic features of SS have been described by multiple authors, however, there are no definitive imaging characteristics that are diagnostic for SS [21][22][23][24]. In fact, in the few cases of intra-articular SS that have been reported, the majority were clinically diagnosed as common benign lesions such as synovitis, synovial chondromatosis, and Pigmented Villonodular Synovitis (PVNS) [11].…”

Section: Introductionmentioning

confidence: 99%

Primary Intra-Articular Synovial Sarcoma of the Knee: A Report of Two Cases and Review of the Literature

E¹,

P²,

Heare³

et al. 2018

Int J Radiol Imaging Technol

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ond most common soft-tissue sarcoma in children and adolescents, after rhabdomyosarcoma [3].Approximately 80% of primary SS arise in the extremities, most commonly in the para-articular regions, the knee being the most common site. However, true intra-articular origin is extremely rare, accounting for less than 5% of cases [4][5][6][7]. From an oncological standpoint, SS is generally regarded as a high-grade sarcoma characterized by slow tumor growth, and a propensity to invade local structures. These tumors have a 30-60% incidence of metastases, which may sometimes develop more than 5 years after the initial diagnosis [8][9][10][11][12][13].Synovial sarcomas are often diagnosed after surgical excision of misdiagnosed benign lesions. Excision of these masses have shown to leave residual tumor in up to 82% of cases [14]. Low-risk synovial sarcomas in pediatric and adolescent patients treated with surgical excision alone show 72% -90% event-free survival at 5 years [15,16]. Intermediate and high risk tumors treated with surgery alone have a more variable 5-year survival between 36% -76%, which raises the need for adjuvant treatment [17]. Synovial sarcoma is relatively chemosensitive within the class of soft tissue sarcomas. A study of 313 cases of synovial sarcomas showed a 27.8% response to chemotherapy compared to 18.8% of other soft tissue sarcomas [18]. Ifosfamide and doxorubicin are the most efficacious chemotherapies for this tumor and have shown to result in 60% survival at 5 years in the absence of surgical excision. Chemotherapy combined with surgical excision and radiation therapy increases overall survival to 80-95% after 3 years [19,20]. AbstractCase: We highlight two cases of primary intra-articular lesions with imaging consistent with Pigmented Villonodular Synovitis (PVNS) and synovial chondromatosis. These benign neoplasms are typically treated with arthroscopic synovectomy. However fluid insufflation of the knee joint in the setting of intra-articular malignancies can dramatically change treatment options. Conclusion:Isolated intra-articular masses in the knee should have careful consideration of the differential diagnosis. These cases highlight the importance of adhering to diagnostic and treatment algorithms for the management of soft tissue masses to avoid potentially catastrophic complications. These cases support the consensus that arthroscopic excisional biopsy is not indicated as the primary procedure for an intra-articular soft tissue mass of unknown etiology.

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MR imaging of synovial sarcoma.

Cited by 124 publications

References 3 publications

Magnetic Resonance Imaging of Synovial Sarcoma

Magnetic Resonance Imaging of Synovial Sarcoma

Soft Tissue Sarcomas

Primary Intra-Articular Synovial Sarcoma of the Knee: A Report of Two Cases and Review of the Literature

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