MRI appearance of COVID-19 infection

Langenbach, M; Hokamp, Nils Große; Persigehl, Thorsten; Bratke, Grischa

doi:10.5152/dir.2020.20152

Cited by 17 publications

(14 citation statements)

References 3 publications

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“…There are also two case reports in the literature regarding the MRI findings of COVID-19. The first belonged to a 47-year-old male patient and both parenchymal consolidation and pleural effusion was demonstrated using MRI ( 13 ). The other case report described a 33-year-old male patient, who was shown to have parenchymal ground-glass densities and consolidations successfully revealed by MRI ( 14 ).…”

Section: Discussionmentioning

confidence: 99%

Thorax Magnetic Resonance Imaging Findings in Patients with Coronavirus Disease (COVID-19)

2020

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Rationale and Objectives: The aim of this study was to compare the findings found in thorax computed tomography (CT), which is increasingly used in the diagnosis of the important public health problem of coronavirus disease (COVID-19), and the findings of magnetic resonance imaging (MRI) as an important diagnostic alternative. Materials and Methods: Thirty-two patients diagnosed with COVID-19 who underwent thorax CT for COVID pneumonia and MRI for any reason within 24 hours after CT were included in the study. The number of lobes affected, number of lobes containing ground-glass opacities and consolidation, number of nodules, distribution of lesions (central, peripheral, or diffuse), lobes with centrilobular nodular pattern, and the presence of pleural effusion were recorded separately for both imaging methods. Results: Seventeen of the patients were female (53%) and 15 were male (47%). The mean age of the patients was 60.5 (range, 20À85) years. A total of 31 patients (96%) had signs of pneumonia on CT. The most common finding in CT was ground-glass opacities in 29 patients (90.6%), followed by consolidation in 14 patients (43.75%). Both consolidation and ground-glass opacities were also observed in MRI in all of these patients. Nodules were detected in 12 patients (37.5%) on CT and 11 patients (34.4%) on MRI. The sensitivity and specificity of MRI in nodule detection were calculated as 91.67% and 100%, respectively. Conclusion: Although thorax CT is widely used in the imaging of COVID-19 infection, due to its advantages, MRI can also be used as an alternative diagnostic tool.

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Section: Discussionmentioning

confidence: 99%

Thorax Magnetic Resonance Imaging Findings in Patients with Coronavirus Disease (COVID-19)

2020

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“…Reports of magnetic resonance imaging (MRI) on diagnosing COVID-19 cases are lacking. Only one study was found to describe the MRI of a patient infected with COVID-19 [86]. The MRI of a patient infected with COVID-19 demonstrated bilateral multilobar focal lung infiltrations, several of which were inhomogeneous with peripheral preference, and some demonstrated direct contact to the visceral pleura, sparing the subpleural space [86].…”

Section: Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%

“…Only one study was found to describe the MRI of a patient infected with COVID-19 [86]. The MRI of a patient infected with COVID-19 demonstrated bilateral multilobar focal lung infiltrations, several of which were inhomogeneous with peripheral preference, and some demonstrated direct contact to the visceral pleura, sparing the subpleural space [86]. Nevertheless, according to the American College of Radiology guidelines, practitioners should not perform MRI scans on patients who test positive for COVID-19 or those who are suspected of being infected.…”

Section: Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%

Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2

Younes

Al-Sadeq

Al-Jighefee

et al. 2020

Viruses

364

371

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The recent outbreak of the Coronavirus disease 2019 (COVID-19) has quickly spread worldwide since its discovery in Wuhan city, China in December 2019. A comprehensive strategy, including surveillance, diagnostics, research, clinical treatment, and development of vaccines, is urgently needed to win the battle against COVID-19. The past three unprecedented outbreaks of emerging human coronavirus infections at the beginning of the 21st century have highlighted the importance of readily available, accurate, and rapid diagnostic technologies to contain emerging and re-emerging pandemics. Real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) based assays performed on respiratory specimens remain the gold standard for COVID-19 diagnostics. However, point-of-care technologies and serologic immunoassays are rapidly emerging with high sensitivity and specificity as well. Even though excellent techniques are available for the diagnosis of symptomatic patients with COVID-19 in well-equipped laboratories; critical gaps still remain in screening asymptomatic people who are in the incubation phase of the virus, as well as in the accurate determination of live viral shedding during convalescence to inform decisions for ending isolation. This review article aims to discuss the currently available laboratory methods and surveillance technologies available for the detection of COVID-19, their performance characteristics and highlight the gaps in current diagnostic capacity, and finally, propose potential solutions. We also summarize the specifications of the majority of the available commercial kits (PCR, EIA, and POC) for laboratory diagnosis of COVID-19.

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“…An increasing number of case reports have confirmed visualization of incidental findings related to COVID-19 pneumonia in individuals who underwent MRI of the head and neck or chest for other clinical indications. 49 , 50 , 51 , 52 , 53 Thus far, three studies have attempted to formally compare the ability of pulmonary MRI to resolve characteristic features of COVID-19 pneumonia against conventional chest CT. In a preliminary case series of eight patients, Torkian et al demonstrated visualization of GGOs, consolidation, reticulation, and a reverse halo sign on multiple MRI sequences.…”

Section: Mrimentioning

confidence: 99%

Imaging of COVID-19: CT, MRI, and PET

Fields

Demirjian

Dadgar

et al. 2021

Seminars in Nuclear Medicine

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Soon after reports of a novel coronavirus capable of causing severe pneumonia surfaced in late 2019, expeditious global spread of Severe Acute Respiratory Distress Syndrome Coronavirus 2 (SARS-CoV-2) forced the World Health Organization to declare an international state of emergency. Although best known for causing symptoms of upper respiratory tract infection in mild cases and fulminant pneumonia in severe disease, Coronavirus Disease 2019 (COVID-19) has also been associated with gastrointestinal, neurologic, cardiac, and hematologic presentations. Despite concerns over poor specificity and undue radiation exposure, chest imaging nonetheless remains central to the initial diagnosis and monitoring of COVID-19 progression, as well as to the evaluation of complications. Classic features on chest CT include ground-glass and reticular opacities with or without superimposed consolidations, frequently presenting in a bilateral, peripheral, and posterior distribution. More recently, studies conducted with MRI have shown excellent concordance with chest CT in visualizing typical features of COVID-19 pneumonia. For patients in whom exposure to ionizing radiation should be avoided, particularly pregnant women and children, pulmonary MRI may represent a suitable alternative to chest CT. Although PET imaging is not typically considered among first-line investigative modalities for the diagnosis of lower respiratory tract infections, numerous reports have noted incidental localization of radiotracer in parenchymal regions of COVID-19-associated pulmonary lesions. These findings are consistent with data from Middle East Respiratory Syndrome-CoV cohorts suggesting an ability for 18 F-FDG PET to detect subclinical infection and lymphadenitis in subjects without overt clinical signs of infection. Though highly sensitive, use of PET/CT for primary detection of COVID-19 is constrained by poor specificity, as well as considerations of cost, radiation burden, and prolonged exposure times for imaging staff. Even still, decontamination of scanner bays is a time-consuming process, and proper ventilation of scanner suites may additionally require up to an hour of downtime to allow for sufficient air exchange. Yet, in patients who require nuclear medicine investigations for other clinical indications, PET imaging may yield the earliest detection of nascent infection in otherwise asymptomatic individuals. Especially for patients with concomitant malignancies and other states of immunocompromise, prompt recognition of infection and early initiation of supportive care is crucial to maximizing outcomes and improving survivability.

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MRI appearance of COVID-19 infection

Cited by 17 publications

References 3 publications

Thorax Magnetic Resonance Imaging Findings in Patients with Coronavirus Disease (COVID-19)

Thorax Magnetic Resonance Imaging Findings in Patients with Coronavirus Disease (COVID-19)

Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2

Imaging of COVID-19: CT, MRI, and PET

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