MRI features and categories of neurobrucellosis: A pooled review

Jiang, Changqin; Shen, Lianfang; Feng, Qiang; Fang, Wei; Jiang, Ruisheng; Zhang, Wanwei; Ma, Zhuo

doi:10.1016/j.jrid.2018.02.001

Cited by 6 publications

(2 citation statements)

References 16 publications

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“…Neuroimaging of NB has a wide range of findings, from normal to meningitis, meningoencephalitis, demyelinating, abscess, and very rare cases of pseudotumor 14 , 15 …”

Section: Discussionmentioning

confidence: 99%

A case series of pediatric neurobrucellosis: a rare complication to a common disease

Mohammed

Ezzatly

Siddiq

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction and importance: Neurobrucellosis (NB) is a rare complication of the most common zoonotic infection worldwide. Meningitis and encephalitis are the most common manifestations. While it is endemic in many countries, it is frequently misdiagnosed due to its nonspecific presentations, and it requires a high index of suspicion and special care to be cured. Case presentation: The first case is from a rural area and presented with a prolonged fever associated with profuse sweating, which was complicated later by headache and sudden left-sided weakness associated with urine incontinence without signs of meningeal irritation. Laboratory and radiological tests confirmed the diagnosis of NB after other cerebral infections were ruled out, and the patient received the full brucella regimen and recovered well. The second patient presented with a gradual onset of fever that did not respond to conventional treatment. Days later, his condition was complicated by a convulsion that was not preceded by an aura and was not accompanied by symptoms of weakness, increased intracranial pressure, or sphincteric disturbances. He has a history of drinking raw milk, and tests for brucella were positive, ruling out other intracranial infections and masses. He received full brucella treatment and showed good recovery. Conclusion: A patient from an endemic area who has a prolonged fever and neurological symptoms should be considered positive for NB until it is ruled out.

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“…Neuroimaging of NB has a wide range of findings, from normal to meningitis, meningoencephalitis, demyelinating, abscess, and very rare cases of pseudotumor 14 , 15 …”

Section: Discussionmentioning

confidence: 99%

A case series of pediatric neurobrucellosis: a rare complication to a common disease

Mohammed

Ezzatly

Siddiq

et al. 2023

Annals of Medicine &Amp; Surgery

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“…(type V) Pseudotumor is also a rare type and could be located in the brain or intramedullary / extramedullary spinal cord. In MRI it is presented with uniform low signal in T1WI and high signal in T2WI with significant enhancement in the post-contrast T1WI [13].…”

Section: Neurobrucellosis May Have Widely Variable Manifestationsmentioning

confidence: 99%

Diffuse Neurobrucellosis of Cerebellum, Brainstem, Spinal Cord, and Cauda Equina: A case report and Literature review

Yazdi¹,

Moosavi²,

Alesaeidi³

et al. 2022

Radiology Case

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Neurobrucellosis is an uncommon serious complication of brucellosis. Diagnosis of neurobrucellosis could be difficult due to non-specific clinical and radiological findings. So, in endemic regions, neurobrucellosis should be included in the differential diagnosis list of patients with recent neurological disorders. We report an unusual case of neurobrucellosis with neurologic deficits in the central and peripheral nervous system and MRI lesions in the brainstem, spinal cord, and nerve roots Also, related articles are reviewed in the discussion section.

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Pediatric neurobrucellosis: a systematic review with case report

Dhar

Jaipuriar

Samim

et al. 2022

Journal of Tropical Pediatrics

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Pediatric neurobrucellosis represents a common anthropozoonosis in endemic areas but only anecdotal reports are available till date. Using appropriate search terms in the database platforms of MEDLINE, SCOPUS and Web of Sciences, we performed a systematic review of all the cases of pediatric neurobrucellosis published in the medical literature till date, in the light of a case report. The protocol was registered under PROSPERO (CRD42022333907). Our search strategy yielded 187 citations of which 51 citations were included. A total of 119 cases were reviewed. Of these cases, eight of them had insufficient data. The most common presentation was meningitis with or without encephalitis (n = 79, 71.2%). A high prevalence of cranial neuropathies (n = 22, 20.7%) was observed in the pediatric population in which abducens palsy was the most common (n = 9, 8.1%). Diagnosis was based on multimodal investigations including standard agglutination test (n = 44, 39.6%), Rose Bengal test (n = 37, 33.3%), blood culture (n = 23, 20.7%), serology (n = 20, 18.0%) and cerebrospinal fluid (CSF) culture (n = 11, 9.9%). Rifampicin-based triple drug regimen was the most commonly employed (83/102, 81.4%). Pediatric neurobrucellosis was associated with greater frequency of sequalae (5.4%), deafness (2.7%) and mortality (2.7%), when compared to that of general population. Neurobrucellosis mimics neuro-tuberculosis in various aspects. The review highlights several unique aspects of this entity in children. A high index of suspicion can ensure prompt diagnosis, timely initiation of management and favorable outcomes.

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MRI features and categories of neurobrucellosis: A pooled review

Cited by 6 publications

References 16 publications

A case series of pediatric neurobrucellosis: a rare complication to a common disease

A case series of pediatric neurobrucellosis: a rare complication to a common disease

Diffuse Neurobrucellosis of Cerebellum, Brainstem, Spinal Cord, and Cauda Equina: A case report and Literature review

Pediatric neurobrucellosis: a systematic review with case report

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