MRI of the Knee in Rheumatoid Arthritis

Yamato, Minoru; Tamai, Kazuya; Yamaguchi, Takehiko; Ohno, Wataru

doi:10.1097/00004728-199309000-00022

Cited by 102 publications

(49 citation statements)

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“…Intravenous injection of contrast agent helps to delineate the inflamed synovial membrane but does not identify fibrotic subsynovium with low vascularity and no edema. This type of synovium would be expected to show very low post-contrast enhancement and relatively later after Gd injection, due to 1036 The patients found a lower level of noise and claustrophobia and more comfortable positioning in E-MRI than in highfield MRI the differences in enhancement rate between active and inactive pannus [24,25]. Consequently, it is not included in the measured area on post-Gd images.…”

Section: Discussionmentioning

confidence: 99%

MRI of the arthritic small joints: comparison of extremity MRI (0.2 T) vs high-field MRI (1.5 T)

et al. 2001

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The aim of this study was to compare the diagnostic capabilities of extremity MRI (E-MRI) with high-field MRI in arthritic small joints, and to evaluate the patients' acceptance and perceptions of the two MR systems. One hundred three patients (group 1 = 28 patients with RA < 3 years, group 2 = 25 patients with reactive and psoriatic arthritis and mixed connective tissue disease, group 3 = 25 patients with rheumatoid arthritis (RA) more than 3 years and group 4 = 25 patients with arthralgia) underwent dedicated E-MRI and high-field MRI of the wrist and finger joints. Coronal short tau inversion recovery and transversal 3D T1-weighted images before and after gadodiamide (Gd) were performed in both cases to outline the volume of the synovial membrane (Vsm) and to evaluate joints with enhancement, effusion, bone edema, and erosions. Investigators blinded to the clinical findings evaluated the images. Patients' compliance and acceptance of E-MRI and high-field MRI were evaluated. The median Vsm obtained on E-MRI did not differ significantly from that obtained on high-field MRI. Vsm = 1 ml (E-MRI) and 1.1 ml (high-field MRI) before Gd and Vsm = 0.1 ml (E-MRI) and 0 ml (high-field MRI) after Gd (Wilcoxon test, p > 0.05). The difference in agreement was 8% for joint enhancement, 2% for joint effusion, 3% for bone edema, and 4% for bone erosions. Of the patients, 64% preferred E-MRI due to more comfortable positioning and less claustrophobia and noise. Extremity MRI of the small arthritic joints is comparable to high-field MRI and more readily accepted than high-field MRI by this patient group.

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Section: Discussionmentioning

confidence: 99%

MRI of the arthritic small joints: comparison of extremity MRI (0.2 T) vs high-field MRI (1.5 T)

et al. 2001

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“…Thus, the theoretical maximum interstitial concentration after an intravenous dose of 0.3 mmol/kg, or 0.21-0.23 l/kg, would be 1.3-1.4 mmol/l (14). The intraarticular gadolinium concentration measured after intravenous administration of Gd-DTPA or Gd-DOTA 0.1 mmol/kg body weight is 0.029-0.44 mmol/l (14,(52)(53)(54). These values are lower than expected based on a uniform distribution in the extracellular space because the contrast medium is rapidly excreted by the renal system and only the synovial membrane of the joint capsule can be regarded as a diffusing tissue (14,(52)(53)(54).…”

mentioning

confidence: 99%

Comparison study of intraarticular and intravenous gadolinium-enhanced magnetic resonance imaging of cartilage in a canine model

et al. 2008

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“…Recently, there have been several reports about the usefulness of contrast-enhanced MRI for early diagnosis of RA [4,6,8,10,12,16,18,19,22]. In a study by McQueen et al [12] MRI revealed carpal erosions in 45% and synovitis in 70% of a group of RA patients at 4 months from the onset of symptoms, only 15% of whom had erosions on plain radiographs [11].…”

Section: Discussionmentioning

confidence: 99%

Maximum intensity projection as a tool to diagnose early rheumatoid arthritis

et al. 2008

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In this study, we investigated the usefulness of contrast-enhanced MRI with maximum intensity projection (MIP) as a convenient tool for detecting early rheumatoid arthritis (RA). A total of 21 patients with undiagnosed arthritis of the hands at the initial visit were enrolled in a prospective study over a 1-year period. The number of swollen joints found during physical examination at this first visit, the results of serological tests and the number of synovitis joints diagnosed on MIP images were compared between the RA group and non-RA group. Of the 21 patients, 17 (81%) from the initial study who were followed up for an additional 1 year entered this study. Of these, 5 met the conditions for diagnosis of RA during follow-up, and 12 did not. MIP images were used to review the arthritis of RA patients, and a significant difference was found in the number of synovitis inflammations detected with MIP images when compared with findings after physical examinations. The two criteria of positive CARF and/or anti-CCP antibody and symmetrical synovitis in bilateral hands on MIP images allowed the prediction of RA with 100% sensitivity and 75% specificity. Thus, MIP is a useful tool for making early diagnosis of RA because it yields clear visualization even with just one image.

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MRI of the Knee in Rheumatoid Arthritis

Cited by 102 publications

References 0 publications

MRI of the arthritic small joints: comparison of extremity MRI (0.2 T) vs high-field MRI (1.5 T)

MRI of the arthritic small joints: comparison of extremity MRI (0.2 T) vs high-field MRI (1.5 T)

Comparison study of intraarticular and intravenous gadolinium-enhanced magnetic resonance imaging of cartilage in a canine model

Maximum intensity projection as a tool to diagnose early rheumatoid arthritis

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