MRI with Gd-DTPA in tumours of larynx and hypopharynx

Vogl, Th.; Steger, W.; Grevers, G.; Schreiner, M.; Dresel, S.; Lissner, J.

doi:10.1007/bf00540106

Cited by 16 publications

(5 citation statements)

References 13 publications

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“…Based on the literature, MRI appears to be more suitable than CT in predicting neoplastic cartilage invasion [6,9,12,13,39]. However, it has still not been determined which imaging modality, CT or MRI, should be used in the pretherapeutic staging of laryngeal cancer.…”

Section: Introductionmentioning

confidence: 99%

Staging of laryngeal cancer: Endoscopy, computed tomography and magnetic resonance versus histopathology

Zbären

Becker

Läng³

1997

Eur Arch Otorhinolaryngol

108

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An accurate pretherapeutic staging of laryngeal cancer is required for optimal treatment planning and for evaluation and comparison of the results of different treatment modalities. In this study, 45 consecutive patients with neoplasms of the larynx, treated surgically, were included in a prospective pretherapeutic staging protocol that included indirect laryngoscopy, direct microlaryngoscopy, contrast-enhanced computed tomography (CT) and Gd-DTPA-enhanced magnetic resonance imaging (MRI). The surgical specimens were cut in whole-organ slices parallel to the plane of the axial CT and MR images. The histologic findings were then compared with clinical findings, CT and MRI. These findings showed that clinical evaluation failed to identify tumor invasion of the laryngeal cartilages and extralaryngeal soft tissues, resulting in a low staging accuracy (55%). Many pT4 tumors were clinically understaged. The combination of clinical/endoscopic evaluation and either CT or MRI resulted in a significantly improved staging accuracy (80% vs 87%, respectively). MRI was significantly more sensitive but less specific than CT in detecting neoplastic cartilage invasion. MRI tended to overestimate neoplastic cartilage invasion to possibly result in overtreatment, while CT was found to underestimate neoplastic cartilage invasion and could lead to inadequate therapeutic decisions.

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Section: Introductionmentioning

confidence: 99%

Staging of laryngeal cancer: Endoscopy, computed tomography and magnetic resonance versus histopathology

Zbären

Becker

Läng³

1997

Eur Arch Otorhinolaryngol

108

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“…As in CT, the domain of MR is the evaluation of deep tumoral extension because of the general superiority of endoscopic methods at the level of the mucosa [1,26,27]. On T1-weighted SE/TSE images, tumor and muscle are darker as compared with fatty tissue; thus, tumoral infiltration can be well demarcated against fat on precontrast images.…”

Section: Magnetic Resonance (General Pathological Aspects)mentioning

confidence: 99%

“…Mineralization may be asymmetric making determinations based on simple comparison of one side to the other unreliable. The MR criteria for cartilage invasion are lower signal intensity on T1-weighted images, higher signal on T2-weighted images [31], areas of enhancement within cartilage adjacent to the tumor [26], and tumor on both sides of the cartilage (extralaryngeal tumor) resulting in an overall sensitivity of 89%, a nega- Fig. 6 A CT scan of a 33-year-old man with a T3 supraglottic squamous cell carcinoma.…”

Section: Laryngeal Skeletonmentioning

confidence: 99%

Current concepts in imaging of laryngeal and hypopharyngeal cancer

2002

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In adjunct to direct laryngoscopy, CT and/or MRI are needed for an accurate staging of laryngeal and hypopharyngeal carcinomas because both cross-sectional imaging modalities are known to reliably evaluate deep tumor infiltration. Except for the clinical background, this article reviews technical aspects of CT and MRI, the pathologic appearance of laryngeal and hypopharyngeal carcinomas, and therapeutically relevant diagnostic aspects.

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“…

nigen Radio-/Chemotherapie und die Planung der operativen Defektrekonstruktion durch verschiedene Lappenplastiken im Vordergrund.Eine korrekte T-Klassifikation durch die klinische Untersuchung in Kombination mit der Panendoskopie gelingt bei Larynxtumoren nur in 52-64% der Fälle, die Treffsicherheit läßt sich mit der CT (80-88%) und MRT (85-86%) deutlich steigern [1,18,19,20,21]. Hauptursache dafür ist, daß submukös wachsende Tumoranteile endoskopisch nicht erkannt werden, tiefe Kompartimente wie der präepiglotti-sche und parapharyngeale Raum entgehen der Diagnostik durch die panendoskopische Spiegelung in Vollnarkose.

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Morphologische und funktionelle Diagnostik der Kopf-Hals-Region mit Mehrzeilen-Spiral-CT

Lell

Baum

Koester³

et al. 1999

Der Radiologe

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The exact determination of tumor margins is mandatory for modern therapy concepts of limited surgery. High resolution datasets are basis for reformations in arbitrary planes, making additional coronal scanning not necessary. Functional imaging of the larynx and hypopharynx improve the diagnostic accuracy of CT, a short scan time is necessary to reduce motion artifacts. Conclusive assessment of tumor infiltration, lymphatic spread and functional alterations is improved with MSCT.

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MRI with Gd-DTPA in tumours of larynx and hypopharynx

Cited by 16 publications

References 13 publications

Staging of laryngeal cancer: Endoscopy, computed tomography and magnetic resonance versus histopathology

Staging of laryngeal cancer: Endoscopy, computed tomography and magnetic resonance versus histopathology

Current concepts in imaging of laryngeal and hypopharyngeal cancer

Morphologische und funktionelle Diagnostik der Kopf-Hals-Region mit Mehrzeilen-Spiral-CT

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