Mucinous adenocarcinoma in association with hidradenitis suppurativa

Alkeraye, Salim; Nguyen, Tegan; Guern, A. Le; Al‐Haddad, Mohammad; Mortier, Laurent

doi:10.1111/ced.13123

Cited by 5 publications

(8 citation statements)

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“…They are usually associated with chronic inflammation and manifest as persistent symptoms, regardless of the conventional treatment[ 8 , 9 ]. Most patients present with perianal purulent discharge, a palpable peripheral mass, an ulcer or a recurrent abscess, which are non-specific symptoms regardless of original disease[ 3 , 4 , 9 , 10 ]. Patients with a tumor originating from a perianal fistula have a history of a fistula or persistent disease[ 3 , 11 , 12 ].…”

Section: Discussionmentioning

confidence: 99%

“…Patients with a tumor originating from HS also have a history of HS and symptoms similar to those of patients with a perianal fistula[ 4 , 18 ]. Patients with a tumor originating from HS present with HS for at least 10 years[ 19 , 20 ].…”

Section: Discussionmentioning

confidence: 99%

“…Patients with a tumor originating from HS present with HS for at least 10 years[ 19 , 20 ]. The tumor originating from HS may be located in the perianal region, perineum, and buttocks[ 4 , 20 ]. The most common tumor type originating from HS is squamous adenocarcinoma, but it could be mucinous adenocarcinoma in some cases, in contrast to the tumor types originating from a perianal fistula[ 19 , 20 ].…”

Section: Discussionmentioning

confidence: 99%

“…Patients with mucinous adenocarcinoma involved with an anal fistula undergo APR, similar to patients with Crohn's anal fistula[ 5 , 11 ]. Even if the disease does not involve the anus, most patients with associated HS undergo APR[ 4 , 19 ]. Patients with wide excision underwent reconstructive operations[ 12 , 17 , 28 ].…”

Section: Discussionmentioning

confidence: 99%

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Mucinous adenocarcinoma of the buttock associated with hidradenitis: A case report

Kim

et al. 2020

WJCC

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BACKGROUND Mucinous adenocarcinomas of the buttock are rare and have an uncertain etiology and natural course. They are usually related to chronic anal fistulas, hidradenitis suppurativa, or Crohn's disease. Here, we report a case of mucinous adenocarcinoma associated with hidradenitis and contradictory immunochemistry results. CASE SUMMARY A 62-year-old man complained of recurrent abscesses of the buttock for 3 years. He had several scars and nodules in bilateral buttocks, with purulent discharge. The skin lesions did not appear to originate from the anus. The patient was diagnosed with recurrent abscesses due to hidradenitis suppurativa at the first visit. He showed purulent and subsequent mucin discharge in the first operation and was diagnosed with mucinous adenocarcinoma. Several examinations were performed to determine disease origin and staging. There were no significant findings or evidence of anal fistulas. Hence, he underwent wide local excision and V-Y advancement flap in the second operation. The final diagnosis was mucinous adenocarcinoma without any evidence of anal fistulas. Additional immunochemistry test results were negative for cytokeratin (CK) 7 and positive for CK20 and CDX2 , with a colorectal origin. A pathologist suggested that the disease originated from a chronic anal fistula. The patient has remained free of recurrence for 24 mo. CONCLUSION Although the patient with mucinous adenocarcinoma showed an atypical course, immunochemistry helped detect the disease origin.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Mucinous adenocarcinoma of the buttock associated with hidradenitis: A case report

Kim

et al. 2020

WJCC

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“…We read with interest the case report published by Alkeraye et al . in the July 2017 issue of Clinical and Experimental Dermatology , describing a 61‐year‐old man with hidradenis suppurativa (HS) of the gluteal fold, who developed a mucinous adenocarcinoma on the same skin area …”

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confidence: 99%