Mucinous Appendicular Cystadenocarcinoma and Pregnancy

Abstract

Primary appendicular adenocarcinoma is rare. We report an unusual mucinous appendicular adenocarcinoma during pregnancy. To our knowledge, this is the second reported case in the literature. A mucinous appendicular cystoadenocarcinoma was discovered unexpectedly and coincidentally during a cesarean section performed in term pregnancy. An appendectomy was simultaneously performed, followed by a right hemicolectomy. Given the exceptionally low incidence tumors co-existing with pregnancy, we recommend a careful and complete appendix examination during cesarean and postpartum sterilization, and subsequent removal of tumors should they exist.

Appendiceal adenocarcinoma: Case report of an unexpected mimicker of ectopic pregnancy

“…Primary appendiceal adenocarcinoma is uncommon and is often found incidentally during abdominal or pelvic surgery [2]. In some cases, patients can present with acute appendicitis.…”

“…Appendiceal neoplasms are rare gastrointestinal malignancies, comprising only 0.5% of intestinal cancers [1]. These tumors are often identified during abdominal surgery or as incidental findings on pelvic imaging [2]. During pregnancy, the incidence of malignant neoplasms is low.…”

“…During pregnancy, the incidence of malignant neoplasms is low. While there have been cases of appendiceal malignancies complicating pregnancy, these reports are rare [2][3][4][5]. Over half of these cases involve neuroendocrine tumors, which are commonly identified due to their associated carcinoid syndromic presentation [6,7].…”

Management of appendiceal pseudomyxoma peritonei diagnosed during pregnancy

“…In a review of the literature, there have been 7 previous reports of appendiceal mucinous tumors occurring during pregnancy in the absence of pseudomyxoma peritonei syndrome [ 7 , 11 - 16 ]. Six were appendiceal mucinous tumors confined to the appendix and one non-mucinous appendiceal adenocarcinoma with peritoneal carcinomatosis (Table 1 ).…”