Mucoadjuvant properties of lipo- and glycoconjugated derivatives of oligochitosans

The Effects of β-Glucan on Pig Growth and Immunity

“…The increased mannitol permeability caused by glucan was further studied by Virschevskaya, who found no expected increase of activated T lymphocytes in mesenteric lymph nodes or Peyer’s patches, suggesting some non-immunologic mechanisms [ 19 ].…”

In vitro antitumor activity of heterochitooligosaccharides (Review)

“…The immunostimulatory activity of chitosan and COSs was discussed previously and is studied at present by a number of researchers [32,33]. It was found that chitosan of 70% DD leads to the activation of macrophages (Mcp) and natural killers (NK cells), improves the delayed type hypersensitivity, and induces mitosis in the cells producing interleukins and interferon.…”

Assessment of temozolomide action encapsulated in chitosan and polymer nanostructures on glioblastoma cell lines

“…Chitosan [poly(b-(10/4)-2-amino-2-deoxy-Dglucose)] is a natural cationic polysaccharide derived from chitin, which is copolymer, a glucosamine and an Nacetyl glucosamine units, combined together [12]. Chitosan is being widely used as a pharmaceutical excipient, comprising a series of polymers varying in their degree of deacylation, molecular weight, viscosity, pKa etc.…”