Mucocutaneous Lymph-Node Syndrome and Parainfluenza 2 Virus Infection

Keim, DanielE.; Keller, E; Hirsch, M. S.

doi:10.1016/s0140-6736(77)90990-4

Cited by 18 publications

(4 citation statements)

References 3 publications

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“…Additionally, associations between parainfluenza and Kawasaki disease 46,47 and mucocutaneous lymph-node syndrome have also been reported. In these diseases viral replication within the endothelium may cause vessel injury, which is important in the pathogenesis of vasculitis 48,49 .…”

Section: Resultsmentioning

confidence: 99%

Temporal Association of Streptococcus, Staphylococcus, and Parainfluenza Pediatric Hospitalizations and Hospitalized Cases of Henoch-Schönlein Purpura

Weiss

Klink²,

Luan³

et al. 2010

J Rheumatol

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Section: Resultsmentioning

confidence: 99%

Temporal Association of Streptococcus, Staphylococcus, and Parainfluenza Pediatric Hospitalizations and Hospitalized Cases of Henoch-Schönlein Purpura

Weiss

Klink²,

Luan³

et al. 2010

J Rheumatol

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“…Weiss et al analyzed 3132 hospitalizations for HSP using a database of admission records from 40 children’s hospitals in the United States and reported that hospitalizations for HSP increased when hospitalizations for group A β-hemolytic streptococcus, S. aureus, and HPIV increased [ 33 ]. HPIV can also contribute to other forms of vasculitis, such as Kawasaki disease [ 34 , 35 ].…”

Section: Discussionmentioning

confidence: 99%

An Investigation of the Relationship between Henoch-Schönlein Purpura and Viral Infection in Korea Using the Health Insurance Database

Park,

Jo,

Kim

et al. 2024

JCM

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(1) Background: This study investigated the epidemiology and viral connections of Henoch–Schönlein purpura (HSP) using information from the Korea Disease Control and Prevention Agency and the Health Insurance Review and Assessment database. (2) Method: Between 2016 and 2019, a total of 25,443 patients with HSP were identified, with 51.3% of patients under the age of 20 years and the highest incidence in March. (3) Results: The autoregressive integrated moving average model and Granger causality test were used to analyze the association between the virus positivity detection rate and HSP incidence. (4) Conclusions: The incidence of HSP was associated with rotavirus, bocavirus, parainfluenza virus, and respiratory syncytial virus in individuals under 20 years of age, whereas adenovirus, respiratory syncytial virus, and norovirus were associated with individuals above that age.

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“…In a nationwide survey to identify KD's incidence and viral etiology in patients hospitalized in a 3‐year study period, HPIV was detected in 382 (2.7%) cases 102 . Seroconversion to HPIV‐2 and viral isolation were demonstrated in a patient with KD with a possible causal relationship 103 . Overall, these data demonstrate that the presence of or concurrent HPIV infection in KD patients is not an unusual event, and physicians should not dismiss the diagnosis of KD based on the presence of respiratory symptoms.…”

Section: Methodsmentioning

confidence: 99%

The landscape of extrapulmonary manifestations of human parainfluenza viruses: A systematic narrative review

Farahmand

Malekshahi

Jabbari

et al. 2020

Microbiology and Immunology

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Human parainfluenza virus (HPIV) infection is associated with every kind of respiratory tract illnesses, including the common cold, laryngotracheobronchitis (i.e. croup), tracheobronchitis, bronchiolitis, and pneumonia, in both children and adults. Although HPIVs are common respiratory pathogens, there are increasing reports about extrapulmonary manifestations of HPIVs infection. Each of the HPIVs could produce infection of other organs (central nervous system, heart, myocardium, etc.) in all age groups who are either immunocompetent or immunocompromised. This review aimed at summarizing the available data on clinical manifestations of HPIV infection outside the respiratory tract from 1961 to 2020. The findings support the possibility of extrapulmonary infections that were thought to be due to rare host genetic or immunologic defects in infected patients. These findings highlight the fact that extrapulmonary dissemination of HPIV can occur, but the association is not clearly demonstrated. Our data support the hypothesis that HPIV infection is one of the possible causes of these alterations and may even be the direct cause in some cases.

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Mucocutaneous Lymph-Node Syndrome and Parainfluenza 2 Virus Infection

Cited by 18 publications

References 3 publications

Temporal Association of Streptococcus, Staphylococcus, and Parainfluenza Pediatric Hospitalizations and Hospitalized Cases of Henoch-Schönlein Purpura

Temporal Association of Streptococcus, Staphylococcus, and Parainfluenza Pediatric Hospitalizations and Hospitalized Cases of Henoch-Schönlein Purpura

An Investigation of the Relationship between Henoch-Schönlein Purpura and Viral Infection in Korea Using the Health Insurance Database

The landscape of extrapulmonary manifestations of human parainfluenza viruses: A systematic narrative review

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