Mucoepidermoid carcinoma of the parotid gland: an unusual presentation

Awwad, Ramez J.; Hsu, Jack

doi:10.1016/j.amjoto.2005.11.013

Cited by 6 publications

(3 citation statements)

References 11 publications

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“…[ 9 ] The overall sensitivity and specificity of FNAC in accurately diagnosing salivary lesions are variable, as reported by different authors in the literature. [ 10 11 12 ] The possibility of false-positive or false-negative results can be attributed to the presence of cystic structures formed due to obstruction of the draining ducts in both benign and malignant tumors. [ 11 ] MEC on cytology shows cohesive sheets of tumor cells with squamous differentiation, abundant cytoplasm and intracytoplasmic mucin vacuoles.…”

Section: Discussionmentioning

confidence: 99%

Mucoepidermoid carcinoma - A common neoplasm at an unusual site, mimicking a benign cyst on cytology

Sharma

Khan²,

Valiathan

2022

Journal of Oral and Maxillofacial Pathology

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Mucoepidermoid carcinoma (MEC) is known to be a relatively common neoplasm of the major and minor salivary glands that can secondarily involve skin. The clinical manifestations, diagnostic cytology and histopathology of MEC presenting as a clinically benign periauricular cystic nodule have been analyzed. The challenge of accurate diagnosis can be illustrated by the fact that initially, on cytology, this tumor was misdiagnosed as a benign epidermal inclusion cyst due to the presence of mucin-filled cells which were misinterpreted as cyst macrophages. This case report emphasizes the need to include parotid tumors in the differential diagnosis of all periauricular cyst-like expansions. We also briefly discuss the reasons for false-positive cytology in this case. Delay in accurate diagnosis may result in larger surgical procedures, such as radical neck dissection, that may otherwise be avoided.

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Section: Discussionmentioning

confidence: 99%

Mucoepidermoid carcinoma - A common neoplasm at an unusual site, mimicking a benign cyst on cytology

Sharma

Khan²,

Valiathan

2022

Journal of Oral and Maxillofacial Pathology

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“…The use of fine-needle aspiration (FNA) to aid in the diagnosis is a common and appropriate practice in parotid schwannoma [11,12]. The cytology may reveal spindle-shaped cells with ill-defined cytoplasm, arranged in clusters (Verocay bodies).…”

Section: Discussionmentioning

confidence: 99%

Two rare schwannomas of head and neck

et al. 2014

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Twenty-five to 45 percent of all schwannomas occur in the head and neck. Most of them arise along the vestibular portion of the eighth cranial nerve (acoustic neurinoma). They rarely originate from the peripheral facial nerve or other nerves within the parotid gland. Less than 4% of schwannomas involve the nasal cavity and paranasal sinuses. They arise from the branches of the trigeminal nerve and autonomic nervous system.We report two cases of schwannomas arisng from intraparotid facial nerve and nasal cavity. The first case diagnosed in a 62-year-old-man presented with 2-year-history of painless mass of the parotid gland. The lesion was found to be cystic through the pre operative examinations and investigations. The histology of the specimen retained an intraparotid cystic schwannoma. The second case concerned a 75-year-old-man presented with episodes of nasal obstruction, rhinorrhea, anosmia and headache. Histological study of the specimen showed fusiform cells with strongly and diffusely immunostaining for S100 protein suggesting a schwannoma.Virtual Slideshttp://www.diagnosticpathology.diagnomx.eu/vs/1098335216112242.

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“…Intraoperative frozen section determined that the mass in question was actually mucoepidermoid carcinoma. 5 In HIV-positive patients, the prevalence of BLEL as an etiology of parotid masses can cause further confusion. This diagnostic dilemma may also occur in children, in whom an accurate FNAB can be more difficult to obtain due to patient intolerance.…”

Section: 2mentioning

confidence: 99%