Mucosal Melanoma of the Hard Palate: Surgical Treatment and Reconstruction

Bondi, Stefano; Vinciguerra, Alessandro; Lissoni, Alessandra; Rizzo, Nicola; Barbieri, Diego; Indelicato, Pietro; Abati, S.

doi:10.3390/ijerph18073341

Cited by 3 publications

(1 citation statement)

References 38 publications

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“…Oral mukozal melanomda evreleme Amerikan Kanser Evreleme Birleşik Komitesi tarafından belirlenen kurallar doğrultusunda TNM sınıflaması ile yapılmaktadır (Balch ve ark., 2009). Oral mukozal melanoma evrelemeleri her ne kadar TNM sınıflaması ile yapılsa da kemik, sinir, deri metastazı ya da metastatik lenf nodu varlığında hasta Evre IV kabul edilmektedir (Bondi et al, 2021). Bu da rutin muayenelerde lenf nodu muayenesi gerekliliği ve önemini göstermektedir.…”

Section: Introductionunclassified

Oral Mukozal Melanom: Nadir Görülen Bir Vaka Raporu

AKTÜRK

Taşyapan

Ramazanoğlu

et al. 2023

Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri Ve Araştırmaları Dergisi

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Oral mukozal melanom (oral malign melanom) nadir bir neoplazmdır. Oral melanomların en sık yerleşim yeri diş eti, sert damak ve alveolar krettir. Lezyon sıklıkla belirgin şişlik, dişlerde yer değişikliği, ülserasyon ve kanama şikayetleri ile tespit edilir. Agresif bir davranışı olduğu için 5 yıllık hayatta kalma oranının %33.1 civarında olduğu tahmin edilmektedir. Bu nedenle, bu olgu sunumunun amacı erken tanının önemini vurgulamak, ilgili pigmente lezyonlara daha fazla şüphe ile yaklaşılmasını tavsiye etmektir. 69 yaşında kadın hasta şişlik ve ağrı şikayetleriyle kliniğimize başvurdu. Alınan anamnezde hipertansiyon ve diyabet tanılı hastanın, şişliği son 1-2 aydır fark ettiği öğrenildi. İntraoral muayenede sert damakta, maksiller alveolar krette ve bukkal sulkus alanında pigmente ve ülsere lezyonlar tespit edildi. Radyografik muayene, hastadaki lezyonların sadece yumuşak dokuda lokalize olduğunu ortaya koydu. Biyopsi sonucunda lezyona “malign melanom” tanısı konuldu. Oral mukozal melanom nadir görülen agresif bir tümör olup hayatta kalma oranı çok düşüktür. Klinisyenler oral kavitede sıklıkla karşılaştıkları intraoral pigmente lezyonlara oral mukozal melanom ihtimaline binaen daha çok şüphe ile yaklaşmalıdırlar.

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Section: Introductionunclassified

Oral Mukozal Melanom: Nadir Görülen Bir Vaka Raporu

AKTÜRK

Taşyapan

Ramazanoğlu

et al. 2023

Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri Ve Araştırmaları Dergisi

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Traumatic Neuroma of the Hard Palate Mimicking a Small Salivary Gland Tumor—A Case Report

Nelke,

Janeczek,

Pasicka

et al. 2024

Biomedicines

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In the case of any pathologies arising in the hard palate, it is always important to exclude their possible odontogenic origins. Cone-beam computed tomography is mandatory. In cases where a possible non-teeth-related pathology is confirmed, each clinician should remember possible differential diagnostics. Many small salivary glands between the mucosa and bone are present in this palatal area. Both benign and malignant tumors arising from the small glands, and mucosa of the hard palate, might occur. The case presented here mimics a solid tumor because of the nodule consistency. Because of a healthy palatal mucosa without any erosions or irritations with firm attachment to the submucosal nodule, a possible malignant tumor of small salivary gland origins was suspected in this case. When the tumor diameter is small, an excisional biopsy is required to collect good and representative material for further histopathological evaluation. In most cases, bulky nodules present on the palate are hard on palpation, non-movable, and covered with healthy mucosa. Possible bone infiltrations with mucous membrane ulcerations could manifest a more expansive character of the lesion. In the presented case, an unusual occurrence of a traumatic neuroma without any past traumatic etiology of the palate was first differentiated from the occurrence of adenoid-cystic carcinoma (ACC), pleomorphic adenoma, other benign/malignant small gland tumors, or atypical, fibroma/schwannoma of the palate. This paper presents treatment options for this rare oral neural tumor occurrence in the palate and differential diagnosis between hard palate tumors in a 42-year-old male patient, furthermore highlighting the role of an excisional biopsy as a good source for a tissue sample.

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Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review

Abati,

Sandri,

Finotello

et al. 2024

Cancers

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This paper examines the clinical differentiation of pigmented lesions in the oral mucosa, which poses significant diagnostic challenges across dental and medical disciplines due to their spectrum from benign to potentially malignant conditions. Through a literature review and analysis of clinical cases, this study clarifies current diagnostic methodologies, with an emphasis on differential diagnosis, to provide a practical guide for clinicians. The classification of pigmented lesions, such as endogenous, focal melanocytic, and multifocal pigmentation, based on clinical and histological features, highlights the necessity for a structured and informed approach. A retrospective examination of cases from our oral medicine and pathology clinic, coupled with analysis of photographic and histological records, aids in classifying these lesions. This fosters a better understanding and promotes informed discussions among clinicians, ultimately aiming to enhance early and precise diagnosis, thus improving patient management and outcomes.

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Mucosal Melanoma of the Hard Palate: Surgical Treatment and Reconstruction

Cited by 3 publications

References 38 publications

Oral Mukozal Melanom: Nadir Görülen Bir Vaka Raporu

Oral Mukozal Melanom: Nadir Görülen Bir Vaka Raporu

Traumatic Neuroma of the Hard Palate Mimicking a Small Salivary Gland Tumor—A Case Report

Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review

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