Abstract. This article is dedicated to multilevel quadrature methods for the rapid solution of stochastic partial differential equations with a log-normally distributed diffusion coefficient. The key idea of such approaches is a sparse-grid approximation of the occurring product space between the stochastic and the spatial variable. We develop the mathematical theory and present error estimates for the computation of the solution's moments with focus on the mean and the variance. Especially, the present framework covers the multilevel Monte Carlo method and the multilevel quasi-Monte Carlo method as special cases. The theoretical findings are supplemented by numerical experiments.Key words. multilevel quadrature, PDEs with stochastic data, log-normal diffusion, Karhunen-Loève expansion, finite element method AMS subject classifications. 65N30, 65D32, 60H15, 60H351. Introduction. In this article, we consider multilevel quadrature methods to compute the moments of the solution to elliptic partial differential equations with log-normally distributed diffusion coefficient. The basic idea of the multilevel quadrature is a sparse-grid-like discretization of the underlying Bochner space L 2 P Ω; H 1 0 (D) . The spatial variable is discretized by a classical finite element method whereas the stochastic variable is treated by an appropriately chosen quadrature rule, which naturally leads to a non-intrusive method. Since the problem's solution provides the necessary mixed Sobolev regularity, the approximation errors on the different levels of resolution can be equilibrated in a sparse-grid-like fashion, cf. [8,20,42]. This idea has already been proposed for different quadrature strategies in case of uniformly elliptic diffusion coefficients in [23]. The well-known Multilevel Monte Carlo Method (MLMC), as introduced in [3,15,16,26,27], and also the Randomized Multilevel Quasi-Monte Carlo Method, as introduced in [30], only provide probabilistic error estimates in the mean-square sense. To avoid this drawback, two fully deterministic methods have been proposed in [23], namely the Multilevel Quasi-Monte Carlo Method (MLQMC) and the Multilevel Polynomial Chaos Method (MLPC).The multilevel Monte Carlo method has been considered at first for a log-normal diffusion coefficient in [12] and further been analyzed in [11,40]. However, for deterministic quadrature methods, the log-normal case is much more involved due to the unboundedness of the domain of integration, i.e. R m for some m ∈ N, in combination with the stronger regularity requirements on the integrand. This makes the analysis of the quadrature error difficult. In particular, special regularity results are required which extend those of [2,10,29].For a finite stochastic dimension, we show that the multilevel quasi-Monte Carlo quadrature is feasible also for a log-normal diffusion coefficients if an auxiliary density is introduced.