Multi-Omics Approach in Amelioration of Food Products

Dutta, Bandita; Lahiri, Dibyajit; Nag, Moupriya; Abukhader, Rose; Sarkar, T.; Pati, Siddhartha; Upadhye, Vijay; Pandit, Soumya; Amin, Mohamad Faiz Mohd; Al-Tawaha, Abdel Rahman Mohammad Said; Kumar, M.; Ray, Rina Rani

doi:10.3389/fmicb.2022.955683

Cited by 11 publications

(8 citation statements)

References 141 publications

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“…NASA scientists have also explored microgreens in space due to dynamic properties like the availability of oxygen generation, nitrogen, essential nutrients, and photoactive compounds to enhance the morale of astronauts during stretched stays away from Earth ( Kyriacou et al, 2017 ). Several breeding approaches and multiOmics have been explored to augment the shelf life, developmental rate and nutrient content of vegetables and fruits ( Kalia and Singh, 2018 ; Mathiazhagan et al, 2021 ; Reda et al, 2021 ; Valdes et al, 2021 ; AieseCigliano et al, 2022 ; Chakravorty et al, 2022 ; Dutta et al, 2022 ; Kumari et al, 2022 ; Parmar et al, 2022 ; Sahoo et al, 2022 ; Sharma et al, 2022 ). However, it has been observed in tomatoes that the dominance component was higher than the additive component for shelf life ( Pavan and Gangaprasad, 2022 ).…”

Section: Strategies To Overcome Limitations Of Microgreen Productionmentioning

confidence: 99%

“…Biofortification can be done by understanding the genes, pathways and regulatory networks responsible for absorbing and transporting nutrients and adopting genetic means that involve using the natural germplasm during conventional breeding, genetic engineering (through genetic engineering or production of transgenics) and other OMICS approaches. The significance of multiomics, nutriomics and foodomics have been explained for development of desirable genotypes with potential microgreen related traits (shelf life and nutrient content) those will be also helpful for improvement of breeding cycles ( Kalia and Singh, 2018 ; Mathiazhagan et al, 2021 ; Reda et al, 2021 ; Valdes et al, 2021 ; AieseCigliano et al, 2022 ; Bansal et al, 2022a ; Chakravorty et al, 2022 ; Dutta et al, 2022 ; Kumari et al, 2022 ; Parmar et al, 2022 ; Sahoo et al, 2022 ; Sharma et al, 2022 ).…”

Section: Strategies To Overcome Limitations Of Microgreen Productionmentioning

confidence: 99%

“…Prospective OMICS approaches have been investigated in many plants to improve the desirable traits and elucidated earlier ( AieseCigliano et al, 2022 ; Chakravorty et al, 2022 ; Dutta et al, 2022 ; Gupta, 2022 ; Gupta and Tyagi, 2022 ; Parmar et al, 2022 ; Sharma and Gupta, 2022 ; Singh et al, 2022 ). Re-sequencing activities of whole-genome employing genetic diversity, domestication patterns, evolutionary analysis, population structure, and linkage disequilibrium for chickpea improvement as a result of the technical advancements that upgraded chickpea (an orphan crop) to a potential geneticcrop ( Varshney et al, 2019 ).…”

Section: Integrating Various Omics Approaches For Microgreen Traitsmentioning

confidence: 99%

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Prospects of microgreens as budding living functional food: Breeding and biofortification through OMICS and other approaches for nutritional security

Gupta

Sharma

Singh³

et al. 2023

Front. Genet.

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Nutrient deficiency has resulted in impaired growth and development of the population globally. Microgreens are considered immature greens (required light for photosynthesis and growing medium) and developed from the seeds of vegetables, legumes, herbs, and cereals. These are considered “living superfood/functional food” due to the presence of chlorophyll, beta carotene, lutein, and minerals like magnesium (Mg), Potassium (K), Phosphorus (P), and Calcium (Ca). Microgreens are rich at the nutritional level and contain several phytoactive compounds (carotenoids, phenols, glucosinolates, polysterols) that are helpful for human health on Earth and in space due to their anti-microbial, anti-inflammatory, antioxidant, and anti-carcinogenic properties. Microgreens can be used as plant-based nutritive vegetarian foods that will be fruitful as a nourishing constituent in the food industryfor garnish purposes, complement flavor, texture, and color to salads, soups, flat-breads, pizzas, and sandwiches (substitute to lettuce in tacos, sandwich, burger). Good handling practices may enhance microgreens’stability, storage, and shelf-life under appropriate conditions, including light, temperature, nutrients, humidity, and substrate. Moreover, the substrate may be a nutritive liquid solution (hydroponic system) or solid medium (coco peat, coconut fiber, coir dust and husks, sand, vermicompost, sugarcane filter cake, etc.) based on a variety of microgreens. However integrated multiomics approaches alongwith nutriomics and foodomics may be explored and utilized to identify and breed most potential microgreen genotypes, biofortify including increasing the nutritional content (macro-elements:K, Ca and Mg; oligo-elements: Fe and Zn and antioxidant activity) and microgreens related other traits viz., fast growth, good nutritional values, high germination percentage, and appropriate shelf-life through the implementation of integrated approaches includes genomics, transcriptomics, sequencing-based approaches, molecular breeding, machine learning, nanoparticles, and seed priming strategiesetc.

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Section: Strategies To Overcome Limitations Of Microgreen Productionmentioning

confidence: 99%

Section: Strategies To Overcome Limitations Of Microgreen Productionmentioning

confidence: 99%

Section: Integrating Various Omics Approaches For Microgreen Traitsmentioning

confidence: 99%

See 1 more Smart Citation

Prospects of microgreens as budding living functional food: Breeding and biofortification through OMICS and other approaches for nutritional security

Gupta

Sharma

Singh³

et al. 2023

Front. Genet.

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“…For example, multi-omics data have been successfully applied in the food industry to extend product shelf life, ensure microbial quality control, and improve the health content of products. 2 These data have also been applied in the biomedical 1 and biotechnology 3 industries. Especially when paired with a well-curated reference genome, omics data will enhance our ability to determine causal relationships from cellular manipulations and help us reach standard industrial goals of improved production titre and cell growth.…”

Section: Introductionmentioning

confidence: 99%

Online Omics Platform Expedites Industrial Application of Halomonas bluephagenesis TD1.0

Park

Faulkner

Toogood

et al. 2023

Bioinform Biol Insights

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Multi-omic data mining has the potential to revolutionize synthetic biology especially in non-model organisms that have not been extensively studied. However, tangible engineering direction from computational analysis remains elusive due to the interpretability of large datasets and the difficulty in analysis for non-experts. New omics data are generated faster than our ability to use and analyse results effectively, resulting in strain development that proceeds through classic methods of trial-and-error without insight into complex cell dynamics. Here we introduce a user-friendly, interactive website hosting multi-omics data. Importantly, this new platform allows non-experts to explore questions in an industrially important chassis whose cellular dynamics are still largely unknown. The web platform contains a complete KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway enrichment analysis derived from principal components analysis, an interactive bio-cluster heatmap analysis of genes, and the Halomonas TD1.0 genome-scale metabolic (GEM) model. As a case study of the effectiveness of this platform, we applied unsupervised machine learning to determine key differences between Halomonas bluephagenesis TD1.0 cultivated under varied conditions. Specifically, cell motility and flagella apparatus are identified to drive energy expenditure usage at different osmolarities, and predictions were verified experimentally using microscopy and fluorescence labelled flagella staining. As more omics projects are completed, this landing page will facilitate exploration and targeted engineering efforts of the robust, industrial chassis H bluephagenesis for researchers without extensive bioinformatics background.

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“…Transcriptomics and proteomics are powerful molecular biology techniques that have shown great promise in advancing our understanding of various biological processes, including those related to food safety [7]. These methodologies have contributed significantly to the identification of potential hazards, the assessment of food quality, and the development of strategies to enhance food safety [8]. Transcriptomics involves the analysis of the whole set of RNA transcripts in a cell or organism.…”

mentioning

confidence: 99%