Electrochemical hydrogen production is considered as one of the most significant ways to develop clean energy in the future. Herein, the self‐supporting electrocatalyst of MoS2@Ni(Mn)VO
X
is fabricated on 3D nickel foam (NF) by a facile two‐step electrodeposition approach. The optimal MoS2@Ni(Mn)VO
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electrode shows an ultralow overpotential of 61 mV to achieve a current density of 10 mA cm−2 and a Tafel slope of 35.1 mV dec−1 in 1 m KOH, which is superior to NF, MoS2@NF, NiVO
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, Ni(Mn)VO
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, or MoS2@NiVO
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. The uniformly dispersed coral‐shaped heterostructure exposes more active sites and makes the charge transfer rate faster. The outstanding synergistic effect of MoS2 and transition metal oxides of Ni, Mn, and V also contribute to the enhanced activity of the catalyst. Benefiting from these, MoS2@Ni(Mn)VO
X
shows superior alkaline hydrogen evolution reaction activity and long‐term stability. Herein, a novel catalyst for highly efficient hydrogen evolution in alkaline media is provided.