Multi-residue pesticide analysis in virgin olive oil by nanoflow liquid chromatography high resolution mass spectrometry

Moreno‐González, David; Alcántara-Durán, Jaime; Addona, Silvina M; Beneito‐Cambra, Miriam

doi:10.1016/j.chroma.2018.05.053

Cited by 53 publications

(24 citation statements)

References 35 publications

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“…In addition to PSA, 15 mg MWCNTs (particle size length: 10–50 μ m, outer diameter: 30–60 nm, and specific surface area: 280 m 2 ·g −1 ) was added to the Sin-QuEChERS Nano column. MWCNTs are nano hollow tubes with high mechanical strength, strong acid-base resistance, stronger adsorption, and purification capacity but do not affect the recovery rate of the target substance [ 23 – 25 ]. This experiment shows that the combination of PSA and MWCNTs can effectively remove impurities in the sample, reduce the interference to the target substance, improve the recovery rate of the target substance, and protect the analytical instrument from pollution and damage.…”

Section: Resultsmentioning

confidence: 99%

Rapid Screening of 352 Pesticide Residues in Chrysanthemum Flower by Gas Chromatography Coupled to Quadrupole-Orbitrap Mass Spectrometry with Sin-QuEChERS Nanocolumn Extraction

Wang

Meng

et al. 2022

Journal of Analytical Methods in Chemistry

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To analyze pesticide residues, GC coupled with quadrupole-Orbitrap MS (GC-Orbitrap-MS) has become a powerful tool because of its unique characteristics of accurate mass full-spectrum acquisition, high resolution, fast acquisition rates, and overcoming matrix interference. This paper presents an efficiency evaluation of GC-Orbitrap-MS for identification and quantitation in the 352 pesticide residues analysis of chrysanthemum flowers in full-scan mode. A streamlined pretreatment approach using one-step extraction and dilution was used, which provided high-throughput processing and excellent recovery. The samples were extracted using acetonitrile. The extracted solution was purified by a Sin-QuEChERS Nano column to suppress the matrix in chrysanthemum flowers and determined by GC-Orbitrap-MS. The calibration curves for the 352 pesticides obtained by GC-Orbitrap-MS were linear in the range of 0.5–200 μg·kg−1, with the correlation coefficients higher than 0.99. The limits of detection (LODs) and the limits of quantification (LOQs) for the 352 pesticide residues were 0.3–3.0 μg·kg−1 and 1.0–10.0 μg·kg−1, respectively. The average recoveries in chrysanthemum flower at three levels were 95.2%, 88.6%, and 95.7%, respectively, with relative standard deviations (RSDs) of 7.1%, 7.5%, and 7.2%, respectively. Lastly, the validated method and retrospective analysis was applied to a total of 200 chrysanthemum flower samples bought in local pharmacies. The proposed method can simultaneously detect multipesticide residues with a good performance in qualitative and quantitative detection.

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Section: Resultsmentioning

confidence: 99%

Rapid Screening of 352 Pesticide Residues in Chrysanthemum Flower by Gas Chromatography Coupled to Quadrupole-Orbitrap Mass Spectrometry with Sin-QuEChERS Nanocolumn Extraction

Wang

Meng

et al. 2022

Journal of Analytical Methods in Chemistry

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“…Moreover, due to the use of acetonitrile, the obtained extracts typically coextracted together with a large number of lipids, which may affect the stability and accuracy of the detection system and may reduce the lifetime of columns . Moreno-González used EMR-lipid as an additional cleanup step that removed most coextracted interferences. The innovative EMR-lipid technology removes lipids based on size exclusion and hydrophobic interaction mechanisms and can remove lipids and the matrix with high selectivity and efficiency.…”

Section: Resultsmentioning

confidence: 99%

Simultaneous Determination of Acrylamide, 5-Hydroxymethylfurfural, and Heterocyclic Aromatic Amines in Thermally Processed Foods by Ultrahigh-Performance Liquid Chromatography Coupled with a Q Exactive HF-X Mass Spectrometer

Gao

Qin

Wen

et al. 2021

J. Agric. Food Chem.

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In this study, a rapid and reliable method based on ultrahigh-performance liquid chromatography coupled with Q Exactive HF-X mass spectrometry (UHPLC-QE/MS) was established for the simultaneous quantification and validation of acrylamide, 5-hydroxymethylfurfural, and 14 heterocyclic aromatic amines in thermally processed foods. With the optimization of the pretreatment method, all 16 hazardous compounds with different polarities were simultaneously extracted and purified by one-step purification. By studying various acquisition modes in detail, full MS + PRM detection using an electrospray ionization source in the positive mode gives an excellent-shaped chromatographic peak and thereby achieves a better quantitative ability for analytes in the matrix. This method demonstrated good quantification recovery in the range of 68.85–146.42%. The limits of quantification were within the range from 0.1 to 50 ng/mL. With the method proposed, the simultaneous determination of 16 hazardous compounds in different thermally processed foods was successfully applied. The all-fragment-ion approaches at high resolution have the ability to reduce false-positive peak detections arising from peak alignment software in the detection of samples significantly. The proposed isotope dilution UHPLC-QE/MS method was validated and demonstrated to be sensitive, accurate, and precise for the simultaneous quantification of multiple contaminants in one injection.

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“…The supernatant was subjected to cleanup using EMR‐lipids in d‐SPE. Good recoveries (75‐119%) were obtained for 162 multiclass pesticides .…”

Section: Sample Extraction and Cleanup Methodsmentioning

confidence: 96%

Extraction techniques for pesticide residues analysis in edible oils and role of sorbents in cleanup

Muhammad

Ahad

Mehboob

2020

Separation Science Plus

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Pesticide residue analysis enables researchers to detect the minute quantity of residual pesticides by applying sensitive analytical techniques which include gas chromatography with mass spectrometry and liquid chromatography with mass spectrometry. However, the sample preparation step prior to utilizing these sophisticated techniques is key to achieving the required sensitivity. The present article reviews the significant methods available for sample preparation for pesticide residue analysis in edible oil. Present sample extraction and cleanup section, most common extraction and cleanup techniques such as liquid‐liquid extraction, solid phase extraction/dispersive solid phase extraction and quick, easy, cheap, effective, rugged and safe method are discussed. Since selection of sorbent affects the recovery, matrix effect and rate of false positive and false negatives, hence, special attention has been paid to sorbents required for sample cleanup. Many sorbents are commercially available however their possible interactions with fatty acids and impurities have not been highlighted in literature. The present review not only highlights the role of commonly used sorbents such as florisil, graphitized carbon black, primary secondary amine and octadecyl bonded silicas but also discusses the pros and cons of newly developed sorbents.

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Multi-residue pesticide analysis in virgin olive oil by nanoflow liquid chromatography high resolution mass spectrometry

Cited by 53 publications

References 35 publications

Rapid Screening of 352 Pesticide Residues in Chrysanthemum Flower by Gas Chromatography Coupled to Quadrupole-Orbitrap Mass Spectrometry with Sin-QuEChERS Nanocolumn Extraction

Rapid Screening of 352 Pesticide Residues in Chrysanthemum Flower by Gas Chromatography Coupled to Quadrupole-Orbitrap Mass Spectrometry with Sin-QuEChERS Nanocolumn Extraction

Simultaneous Determination of Acrylamide, 5-Hydroxymethylfurfural, and Heterocyclic Aromatic Amines in Thermally Processed Foods by Ultrahigh-Performance Liquid Chromatography Coupled with a Q Exactive HF-X Mass Spectrometer

Extraction techniques for pesticide residues analysis in edible oils and role of sorbents in cleanup

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