Multi-Switchable Bioelectrocatalysis Based on Semi-Interpenetrating Polymer Network Films Prepared by Enzyme-Induced Polymerization

Zhang, Kaina; Liu, Shuang; Liu, Hongyun

doi:10.1149/2.0461409jes

Cited by 12 publications

(4 citation statements)

References 47 publications

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“…In recent years, switchable bioelectrocatalysis based on a combination of enzymatic reactions and stimuli-responsive films that are modified on the electrode surface has attracted considerable attention among researchers because it can offer a model to better comprehend the activation/deactivation mechanism of enzymatic reactions in real biological systems and can be used to fabricate switchable and tunable biofuel cells, biosensors, and other bioelectronic devices. − A variety of external stimuli have been applied in this area, such as the pH, temperature, electric field, magnetic field, and light . Herein, the multiple-stimuli responsive bioelectrocatalysis systems − have extraordinary advantages over the single-stimulus triggered ones since the addition of new stimuli or dimensions causes the system to become more complicated, making it similar to real biological systems. In addition, on the basis of the multiple-stimuli sensitive bioelectrocatalysis, more elaborate logic-gate networks could be established, which would be helpful to realize information transduction/amplification and to solve some biomedical problems, as well as to achieve data processing/storage at the nanometer-sized or even molecular levels in chemical/biomolecular computing. , …”

Section: Introductionmentioning

confidence: 99%

Multiple-Stimuli Responsive Bioelectrocatalysis Based on Reduced Graphene Oxide/Poly(N-isopropylacrylamide) Composite Films and Its Application in the Fabrication of Logic Gates

Wang

Lian²,

Yao

et al. 2015

ACS Appl. Mater. Interfaces

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In the present work, reduced graphene oxide (rGO)/poly(N-isopropylacrylamide) (PNIPAA) composite films were electrodeposited onto the surface of Au electrodes in a fast and one-step manner from an aqueous mixture of a graphene oxide (GO) dispersion and N-isopropylacrylamide (NIPAA) monomer solutions. Reflection-absorption infrared (IR) and Raman spectroscopies were employed to characterize the successful construction of the rGO/PNIPAA composite films. The rGO/PNIPAA composite films exhibited reversible potential-, pH-, temperature-, and sulfate-sensitive cyclic voltammetric (CV) on-off behavior to the electroactive probe ferrocenedicarboxylic acid (Fc(COOH)2). For instance, after the composite films were treated at -0.7 V for 7 min, the CV responses of Fc(COOH)2 at the rGO/PNIPAA electrodes were quite large at pH 8.0, exhibiting the on state. However, after the films were treated at 0 V for 30 min, the CV peak currents became much smaller, demonstrating the off state. The mechanism of the multiple-stimuli switchable behaviors for the system was investigated not only by electrochemical methods but also by scanning electron microscopy and X-ray photoelectron spectroscopy. The potential-responsive behavior for this system was mainly attributed to the transformation between rGO and GO in the films at different potentials. The film system was further used to realize multiple-stimuli responsive bioelectrocatalysis of glucose catalyzed by the enzyme of glucose oxidase and mediated by the electroactive probe of Fc(COOH)2 in solution. On the basis of this, a four-input enabled OR (EnOR) logic gate network was established.

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Section: Introductionmentioning

confidence: 99%

Multiple-Stimuli Responsive Bioelectrocatalysis Based on Reduced Graphene Oxide/Poly(N-isopropylacrylamide) Composite Films and Its Application in the Fabrication of Logic Gates

Wang

Lian²,

Yao

et al. 2015

ACS Appl. Mater. Interfaces

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“…Fenton‐mediated FRP has been used in a wide range of applications such as template polymerization, bioelectrocatalysis, and graft copolymerization . Fenton chemistry has been extensively employed as a redox initiation system in the graft copolymerization of vinyl monomers (e.g., MMA, acrylamide, vinyl acetate, etc.)…”

Section: Applications Of Fenton Reaction‐initiated Frpmentioning

confidence: 99%

Fenton‐Chemistry‐Mediated Radical Polymerization

Reyhani

McKenzie

et al. 2019

Macromol. Rapid Commun.

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have been developed for the synthesis of polymers with diverse structures (linear, star, cyclic, etc.), compositions ( • mopolymer, gradient, alternating, block, etc.), and functionalities (thiol, amine, etc.). [11] The main mechanism of RDRP which results in controllable polymerization is the establishment of a dynamic equilibrium between the propagating radicals (active polymers) and the dormant species via a reversible activation-deactivation process with rate constants k act. and k deact. , respectively. [7,12] With the emergence of RDRP methods such as atom transfer radical polymerization (ATRP), [13][14][15] nitroxide-mediated polymerization (NMP), [16] and reversible addition-fragmentation transfer (RAFT) [11,17,18] there has been significant effort to control these techniques via different physical and chemical stimuli. [19][20][21][22][23][24][25][26][27] Of these, RAFT holds particular promise due to its compatibility with a diverse range of solvents, monomers, and operating conditions. [11,24,[28][29][30][31][32][33][34][35] Among RDRP methods, one might argue that RAFT is the most similar to traditional FRP, with the simple addition of a thiocarbonylthio-containing compound chain transfer agent (CTA, termed as RAFT agent) [36] that can mediate the polymerization, allowing the synthesis of well-defined polymers (Scheme 1). In fact, RAFT CTAs aid in achieving control of the radical polymerization via reversible addition of the thiocarbonylthio group and rapid fragmentation reactions. [37,38] Therefore, relatively analogous activation/initiation systems such as thermal, [4,11,[28][29][30][31][39][40][41] photo, [2,24,[32][33][34][42][43][44][45][46][47][48][49] enzyme, [5,23,[50][51][52][53][54] and redox [3,[55][56][57][58][59] based radical formation can be employed to initiate both FRP and RAFT processes. Despite the huge advances made in this field, new techniques that can overcome some of the drawbacks of these systems are continuously sought. For example, using a thermal initiator requires a high operating temperature, limiting the possibility for in situ FRP/RAFT methods in biological systems, where temperature control is limited. The rate of visible light-activated RAFT polymerization without using photocatalysts is relatively slow, [34,60] while photocatalysts, e.g. iridium and rutheniumbased ones, [24,61] employed in photo-activated processes are expensive. Moreover, photo-mediated polymerization faces difficulties in terms of the equipment requisite to perform photoinitiation at scale. [29] Redox-responsive polymerization systems have many advantages, including a low activation energy (40-85 kJ mol −1 ), easy and facile control over the polymerization at ambient temperatures, very short induction periods, etc. [56,62] Polymerizations initiated by a redox reaction between an oxidizing and a reducing agent are referred to as "redox polymerizations." [63] Use of Radical PolymerizationIn this review, the power of a classical chemical reaction, the Fenton reaction for initiating radical polymeriza...

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“…After 3 repeating cycles, the CV I pc at the on state was still 2 times more than the off one, suggesting the system still possesses pH-switchable property for the probe. 28 EIS was also performed to investigate the pH-responsive switching behavior of {PAH/PAA} 4 -(PDEA-HRP) films with Fe(CN) 6…”

Section: Characterization Of the Binary Assembly Of {Pah/paa} 4 -(Pde...mentioning

confidence: 99%

Triple-Switchable Biosensors and an AND Logic Gate Based on Binary Assembly of Weak Polyelectrolyte Multilayers and Hydrogel Films

Yao

Luo

Yang

et al. 2016

J. Electrochem. Soc.

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Triple-responsive films with binary architecture for switchable biosensors were designed on electrodes through the combination of the weak polyelectrolyte {PAH/PAA}n (PAH = poly(allylamine hydrochloride), PAA = poly(acrylic acid)) layer-by-layer assembly and chemically polymerized poly(N,N-diethylacrylamide) (PDEA) hydrogel containing horseradish peroxidase (HRP). The films exhibited reversible pH-, thermo-, and sulfate concentration responsively reversible on-off behaviors toward K3Fe(CN)6 in its cyclic voltammetric (CV) response. Taking thermo-switch as an example, at 25°C, CVs showed a large and well-defined peak pair of Fe(CN)63− and the system was at the on state; while at 40°C, the CV peaks were greatly suppressed and the system was at the off state. The bioactivity of HRP enzyme embedded in the films was well maintained and this film system could be further employed to control and modulate the bioelectrochemical reduction of H2O2 by HRP with K3Fe(CN)6 as the mediator in solution. This triple-triggered bioelectrocatalysis based on the binary interface system could be used as a 3-input AND logic gate and demonstrated the potential perspective for fabricating novel multiple factor-switchable biosensors with immobilized enzymes.

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Multi-Switchable Bioelectrocatalysis Based on Semi-Interpenetrating Polymer Network Films Prepared by Enzyme-Induced Polymerization

Cited by 12 publications

References 47 publications

Multiple-Stimuli Responsive Bioelectrocatalysis Based on Reduced Graphene Oxide/Poly(N-isopropylacrylamide) Composite Films and Its Application in the Fabrication of Logic Gates

Multiple-Stimuli Responsive Bioelectrocatalysis Based on Reduced Graphene Oxide/Poly(N-isopropylacrylamide) Composite Films and Its Application in the Fabrication of Logic Gates

Fenton‐Chemistry‐Mediated Radical Polymerization

Triple-Switchable Biosensors and an AND Logic Gate Based on Binary Assembly of Weak Polyelectrolyte Multilayers and Hydrogel Films

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