Multi-walled carbon nanotube modified carbon paste electrode as a sensor for the amperometric detection of l-tryptophan in biological samples

Thomas, Tony; Mascarenhas, Ronald J.; D’Souza, Ozma J.; Martis, Praveen; Dalhalle, Joseph; Swamy, B.E. Kumara

doi:10.1016/j.jcis.2013.03.059

Cited by 94 publications

(32 citation statements)

References 51 publications

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“…However, narrow peace and insufficient accuracy did not allow adequate description of these parts of the calibration curve. Separation of two linear pieces on calibration curves is frequently mentioned for differently modified electrodes and is commonly explained by two types of binding sites on their surface. In this work, higher sensitivity toward ultra‐small Trp concentrations can be described by their interaction with the silver ions in the pores of the coating partially filled with the Ag nanoparticles while higher analyte concentrations preferably interact with the surface of the film.…”

Section: Resultsmentioning

confidence: 99%

“…Modification of the electrodes with mediators decreases working potential and improves performance of the sensor due to electrocatalytic effect and higher specific surface area. Thus, hemin , carbon nanotubes , ferrocene , Au nanoparticles , acetylene black , taken alone or in combination and included in electropolymerized matrices have been successfully used in the assembly of voltammetric sensors for the Trp determination. Although many of the above sensors show excellent sensitivity, the deposition of the sensing layer often involves several steps with rather complicated intermediate treatment of the surface.…”

Section: Introductionmentioning

confidence: 99%

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Glassy Carbon Electrode Modified with Silver Nanodendrites Implemented in Polylactide‐Thiacalix[4]arene Copolymer for the Electrochemical Determination of Tryptophan

et al. 2017

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Glassy carbon electrode (GCE) was modified by new polymeric materials obtained from oligolactides by cross‐linking with tetracarboxylated thiacalix[4]arene in cone, partial cone and 1,3‐alternate configurations and then silver was deposited by potential cycling in the pores of the polymer film. The modified electrode showed highly sensitive and selective signal toward tryptophan which was irreversibly oxidized on the coating due to Ag+ assisted accumulation in the surface layer. The role of macrocycle configuration and conditions for Ag nanodendrites formation are described. Granulation of the polymer films caused by the macrocycles improves both the conditions for silver deposition and tryptophan determination. The electrochemical sensor developed makes it possible to determine from 0.1 to 100 μM of tryptophan with the limit of detection down to 0.03 μM. No interference with oxidation of other amino acids (phenylalanine, histidine, cysteine and tyrosine) was found. The electrochemical sensor developed was validated in the determination of tryptophan sedative medication “Formula of calmness” in the presence of vitamins B5 and B6.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Glassy Carbon Electrode Modified with Silver Nanodendrites Implemented in Polylactide‐Thiacalix[4]arene Copolymer for the Electrochemical Determination of Tryptophan

et al. 2017

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“…In our continual effort to employ CPE and modified CPE for electroanalytical applications [31][32][33][34][35][36][37][38], in the present work, our aim was to fabricate a non-enzymatic sensor for Tyr. To achieve this, we have modified CPE by bulk modifying it using COOH-MWCNTs in the CPE matrix and employed it for the sensitive determination of Tyr in the presence of interfering molecules.…”

Section: Introductionmentioning

confidence: 99%

Electrocatalytic oxidation of l-tyrosine at carboxylic acid functionalized multi-walled carbon nanotubes modified carbon paste electrode

D’Souza

Mascarenhas

Satpati

et al. 2015

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The electrocatalytic oxidation of L-tyrosine (Tyr) was investigated on a carboxylic acid functionalised multiwalled carbon nanotubes modified carbon paste electrode using cyclic voltammetry and amperometry. The surface morphology of the electrodes was studied using field emission (FE)-SEM images, and the interface properties of bare and modified electrodes were investigated by electrochemical impedance spectroscopy (EIS). The influence of the amount of modifier loading and the variation of the pH of the solution on the electrochemical parameters have been investigated. Cyclic voltammetry was carried out to study the electrochemical oxidation mechanism of Tyr, which showed an irreversible oxidation process at a potential of 637.0 mV at modified electrode. The anodic peak current linearly increased with the scan rate, suggesting that the oxidation of Tyr at modified electrode is an adsorption-controlled process. A good linear relationship between the oxidation peak current and the Tyr concentration in the range of 0.8-100.0 μM was obtained in a phosphate buffer solution at pH 7.0 with a detection limit of 14.0± 1.36 nM (S/N=3). The practical utility of the sensor was demonstrated by determining Tyr in spiked cow's milk and human blood serum. The modified electrode showed excellent reproducibility, long-term stability and antifouling effects.

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“…8 Furthermore, intaking the overdose of Try incites the dizziness, drowsiness, loss of appetite, nausea and hepatic disease. 9 The amount of Try present in the blood is very close relation with serotonin and melatonin, thus the Try was essential for mood enhancement, antidepressant and nutraceutical. 10 As a consequence, the researchers are devoted to develop a simple, selective, sensitive and highly efficient method for the determination of Try.…”

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confidence: 99%

A Simple and Rapid Electrochemical Determination of L-Tryptophan Based on Functionalized Carbon Black/Poly-L-Histidine Nanocomposite

Sakthivel

Mutharani

Chen

et al. 2018

J. Electrochem. Soc.

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In the present work, the functionalized carbon black/poly-l-histidine modified glassy carbon electrode (f-CB/PLH/GCE) was fabricated and applied for the amperometric determination of Try. The proposed modified electrode was prepared by non-hazardous, inexpensive, simple electro polymerization method. The successful formation of f-CB/PLH composite was scrutinized by field-emission scanning electron microscopy, transmission electron microscopy, optical microscope, energy dispersive X-ray spectroscopy, Fourier transform infra-red spectroscopy, Raman spectroscopy and electrochemical impendence spectroscopy. Besides, the electrocatalytic activity of the f-CB/PLH composite was examined by cyclic voltammetry and amperometric techniques. Remarkably, the wide linear range responses from 0.025-124.98 μM with the lowest detection limit 0.008 μM and an appreciable sensitivity of 1.126 μA mM −1 cm −2 was obtained. In addition, f-CB/PLH/GCE exhibits the good selectivity in presence of various inorganic, biological and co-existing interfering compounds. Furthermore, the practical feasibility of the sensor electrode was demonstrated in milk and human urine samples.) unless CC License in place (see abstract). ecsdl.org/site/terms_use address. Redistribution subject to ECS terms of use (see 61.220.116.134 Downloaded on 2018-07-12 to IP ) unless CC License in place (see abstract). ecsdl.org/site/terms_use address. Redistribution subject to ECS terms of use (see 61.220.116.134 Downloaded on 2018-07-12 to IP ) unless CC License in place (see abstract). ecsdl.org/site/terms_use address. Redistribution subject to ECS terms of use (see 61.220.116.134 Downloaded on 2018-07-12 to IP B428Journal of The Electrochemical Society, 165 (10) B422-B430 (2018) ) unless CC License in place (see abstract). ecsdl.org/site/terms_use address. Redistribution subject to ECS terms of use (see 61.220.116.134 Downloaded on 2018-07-12 to IP ) unless CC License in place (see abstract). ecsdl.org/site/terms_use address. Redistribution subject to ECS terms of use (see

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Multi-walled carbon nanotube modified carbon paste electrode as a sensor for the amperometric detection of l-tryptophan in biological samples

Cited by 94 publications

References 51 publications

Glassy Carbon Electrode Modified with Silver Nanodendrites Implemented in Polylactide‐Thiacalix[4]arene Copolymer for the Electrochemical Determination of Tryptophan

Glassy Carbon Electrode Modified with Silver Nanodendrites Implemented in Polylactide‐Thiacalix[4]arene Copolymer for the Electrochemical Determination of Tryptophan

Electrocatalytic oxidation of l-tyrosine at carboxylic acid functionalized multi-walled carbon nanotubes modified carbon paste electrode

A Simple and Rapid Electrochemical Determination of L-Tryptophan Based on Functionalized Carbon Black/Poly-L-Histidine Nanocomposite

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