Multicenter Double-Blinded Randomized Controlled Trial of Standard Abdominal Wound Edge Protection With Surgical Dressings Versus Coverage With a Sterile Circular Polyethylene Drape for Prevention of Surgical Site Infections

Abstract

Our trial shows that CWEPs are effective at reducing the incidence of SSIs in elective and clean or clean-contaminated open abdominal surgery.

Effectiveness of Wound-Edge Protectors for Preventing Surgical Site Infections after Open Surgery for Colorectal Disease: A Prospective Cohort Study with Two Parallel Study Groups

“…The German double-blinded, randomized, controlled trial, BaFO, demonstrated that the single-ring WEP significantly reduced the incidence of SSI [9]. In their study, the incidence of SSI in patients with and without a WEP was 17.7 and 25.2% respectively ( p = 0.026).…”

“…Although several studies showed the usefulness of WEPs, they included not only colorectal but also other types of gastrointestinal surgeries [8, 9, 11]. At the same time, racial differences such as BMI should be taken into consideration to interpret the results of clinical trials.…”

“…On the other hand, the use of a WEP is still controversial. Although several studies demonstrated that a WEP reduced SSI in open surgery [9, 10], contradicting results have also been reported [11]. Therefore, a prospective cohort study with 2 parallel study groups to investigate the incidence of SSI after colorectal surgery in Japanese patients was conducted.…”

Metabolism gene signatures and surgical site infections in abdominal surgery

“…Wounds were evaluated daily by a surgeon during the postoperative course until discharge. Postoperative SSI were classified according to the CDC guidelines [5,20]. All patients gave written informed consent and the project was approved by the local Ethics committee of the Technische Universit€ at München, Munich, Germany.…”

Analysis of Complications After Abdominal Surgery on the Colon

“…Имеют значение, но не оказывают статистически значимого влияния на риск развития послеоперационных осложнений: наложение превентивной стомы; возраст больного; наличие сопутствующей патологии; уровень пересечения нижней брыжеечной артерии; дополнительная мобилизация вышележащих отделов толстой кишки; тип формирования анастомоза; гистологический тип новообразования и стадия процесса [10,11].…”