The rapid development of information and communication technology has driven the demand for higher data transmission rates. Multi-core optical fiber, with its ability to transmit multiple signals simultaneously, has emerged as a promising solution to meet this demand. Additionally, due to its characteristics such as multi-channel transmission, high integration, spatial flexibility, and versatility, multi-core optical fibers hold vast potential in sensing applications. However, the manufacturing technology of multi-core fiber is still in its early stages, facing challenges such as the design and fabrication of high-quality cores, efficient coupling between cores, and the reduction of crosstalk. In this paper, an overview of the current status and future prospects of multi-core fiber manufacturing technology has been presented, and their limitations will be discussed. Some potential solutions to overcome these challenges will be proposed. Their potential applications in optical fiber sensing will also be summarized.