Multifocal Ewing Sarcoma of the Foot

Rammal, Hayan; Ghanem, Ismat; Torbey, Paul-Henri; Dagher, Fernand; Kharrat, Khalil

doi:10.1097/mph.0b013e3181647c14

Cited by 8 publications

(4 citation statements)

References 18 publications

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“…The reason includes poor tumor compartmentalization in the foot, which makes adequate resection difficult, and problems with bony and soft tissue reconstruction. Metastasis at presentation is observed in almost 20% to 25% of patients, most commonly in the lung followed by skeletal metastasis [9,13]. In our case, the systemic staging revealed multiple skeletal metastases out of which one of the lesions in the shaft of the femur became symptomatic during the course of management.…”

Section: Discussionmentioning

confidence: 56%

Ewing's Sarcoma of the Talus in an Adolescent Female: An Unusual Case Presentation With Review of Literature

Jalan¹,

Ravi²,

Prasad³

et al. 2022

Cureus

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Ewing's sarcoma is an aggressive primary malignant bone tumor that affects long and flat bones and is commonly seen in children and adolescents. The involvement of the foot especially the talus is an extremely rare entity with less than 15 cases reported in the literature. The rarity and atypical symptoms often lead to delays in diagnosis affecting the prognosis and survival. We present a 14-year-old female with pain and swelling of the left ankle for 18 months. She was being treated previously for an ankle sprain and was later suspected of avascular necrosis of the talus, before presenting to us. Clinicoradiology-pathological workup confirmed the diagnosis of Ewing sarcoma of the talus. Further, the metastatic workup revealed multiple skeletal metastases at the time of diagnosis. The metastatic lesion of the right femur required prophylactic fixation, otherwise, the patient was treated with palliative chemotherapy and radiotherapy. Ewing's sarcoma of the foot involving the talus is extremely rare and is a commonly misdiagnosed entity, affecting the overall prognosis of the patient. A high index of suspicion and a multidisciplinary approach is imperative for its early diagnosis and definitive management.

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Section: Discussionmentioning

confidence: 56%

Ewing's Sarcoma of the Talus in an Adolescent Female: An Unusual Case Presentation With Review of Literature

Jalan¹,

Ravi²,

Prasad³

et al. 2022

Cureus

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“…After a thorough search of published literature, we were able to find 15 reported cases since the first one was published in 1953. Most of the cases are reported as single case reports 2 6–15. It demonstrates the rarity of occurrence of this highly malignant tumour in the talus.…”

Section: Discussionmentioning

confidence: 95%

“…Almost all the reported cases had been managed with limb ablation surgeries or non-surgically combined chemotherapy and radiotherapy regimens. Only a single case report of limb salvage has been reported who underwent total talectomy and replacement of the entire talus with a custom-made three-dimensional printed talar prosthesis 15. Based on the previously reported literature, local dissemination of the disease to surrounding tarsals, difficulty in achieving tumour-free margins, a lower possibility of achieving optimal functional outcomes after limb salvage and availability of good lower limb prosthesis, below-knee amputation followed by adjuvant multidrug chemotherapy seems to be a prudent management plan if limb salvage does not look promising in terms of oncological and functional outcomes.…”

Section: Discussionmentioning

confidence: 99%

Primary Ewing’s sarcoma of the talus

Kantiwal,

Yadav,

Nalwa

et al. 2023

BMJ Case Rep

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Ewing’s sarcoma is a malignant round cell tumour of bones and soft tissues that usually arises from the diaphyseal or meta-diaphyseal parts of long bones and less commonly from flat bones. It occurs rarely in the foot and if occurs, the calcaneus and the metatarsals are commonly involved. We present a case of a young woman diagnosed with primary Ewing’s sarcoma of the talus with local spread to adjacent tarsals and the ankle joint. Ewing’s sarcoma of feet, if present with even a trivial suspicion of spread either locally or distant, makes limb salvage surgery difficult. So, the treatment with radical surgery or by combined chemotherapy and radiotherapy should be considered—keeping in mind the complex anatomy of the foot and the difficulty in achieving tumour-free margins. Based on this experience, she underwent below-knee amputation. The patient received adjuvant chemotherapy and survived with a disease-free survival at the latest follow-up of 1 year.

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“…It occurs in the second decade of life, more common in boys and most frequently involving the calcaneus and the metatarsal bones. 39 MR imaging features are nonspecific and indistinguishable at times from osteomyelitis. MR imaging is, however, helpful in delineating the extent of the tumor with respect to adjacent structures, especially the neurovascular bundle.…”

Section: Bone Tumorsmentioning

confidence: 97%

The Foot and Ankle: MR Imaging of Uniquely Pediatric Disorders

Patel

2009

Magnetic Resonance Imaging Clinics of North America

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Multifocal Ewing Sarcoma of the Foot

Cited by 8 publications

References 18 publications

Ewing's Sarcoma of the Talus in an Adolescent Female: An Unusual Case Presentation With Review of Literature

Ewing's Sarcoma of the Talus in an Adolescent Female: An Unusual Case Presentation With Review of Literature

Primary Ewing’s sarcoma of the talus

The Foot and Ankle: MR Imaging of Uniquely Pediatric Disorders

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