Multifocal tuberculosis verrucosa cutis of 60 years duration

Damevska, Katerina; Gocev, Gorgi

doi:10.1016/j.ijid.2013.08.002

Cited by 5 publications

(7 citation statements)

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“…The lesions of verrucous TB are single, painless, and in areas that are prone to traumas, as occurred in our patients with leg or foot injury background (Fig. ) . Historically, they are related to handling infectious material, especially in some professional groups, and also attributed to walking barefoot …”

Section: Discussionmentioning

confidence: 65%

“…6). [45][46][47][48] Historically, they are related to handling infectious material, especially in some professional groups, and also attributed to walking barefoot. 2,36,49 Our group tend to regard a granulomatous lobular or septolobular panniculitis (with or without vasculitis) in the setting of a clinical, epidemiological, and/or microbiological diagnosis of tuberculosis as EIB, which was an important clinical form in our study.…”

Section: Discussionmentioning

confidence: 99%

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Cutaneous tuberculosis in Rio de Janeiro, Brazil: description of a series of 75 cases

et al. 2019

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Background Brazil is one of the highest tuberculosis (TB) burden countries of the world. Cutaneous tuberculosis (CTB) is a rare form of extrapulmonary manifestation of tuberculosis. This study aimed to describe the clinico‐evolutive, laboratory and therapeutic aspects of CTB cases among patients from a cohort with TB in Rio de Janeiro, Brazil. Methods Cases of diagnosed CTB with microbiologic confirmation or clinical response to anti‐tuberculous treatment associated with positive smear or histopathological findings between the years 2000 and 2016 were selected. Results Seventy‐five patients with CTB were included, most were women (58.7%) with a median age of 42 years. CTB diagnosis was based on culture in only 42.7% of the cases. Scrofuloderma represented 50.7% of the cases, followed by erythema induratum of Bazin (EIB) (18.7%), tuberculous gumma (13.3%), lupus vulgaris (8%), TB verrucosa cutis (4%), orificial TB (2.7%) and associated forms (2.7%). Other TB presentations were pulmonary (22.7%), mammary (6.6%) and osteoarticular (4%). All patients who completed the treatment (97.3%) had their lesions healed. Only two patients (2.6%) needed to change the therapy due to adverse reactions. Fifty percent of EIB patients presented recurrence. Conclusions These data highlight the diversity of CTB presentations and the importance of the skin to assist in early identification and treatment of TB. More studies are necessary to improve the knowledge on EIB for a better approach towards these patients, mainly in cases of recurrence.

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Section: Discussionmentioning

confidence: 65%

Section: Discussionmentioning

confidence: 99%

Cutaneous tuberculosis in Rio de Janeiro, Brazil: description of a series of 75 cases

et al. 2019

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“…The overall sensitivity was found to be 73%. 15 A recent study from India showed that the sensitivity of DNA PCR is 25% in the diagnosis of cutaneous tuberculosis [12] [In the event of inconclusive specific tests, the diagnosis is based on correlation between clinical appearance and histopathological findings along with clinical response following antituberculous treatment [13] To the best of our knowledge only two such cases of multifocal tuberculosis verrucosa cutis had been reported earlier in immunocompetent and otherwise healthy individuals [14,15]. Prasad et al in 2002 reported a similar case with multifocal involvement but the patient had microcytic normochromic anemia with a hemoglobin 5.6 g% [16].…”

Section: Discussionmentioning

confidence: 99%

Multifocal tuberculosis verrucosa cutis

Chahar

Dhali²,

D’Souza³

2015

Dermatology Online Journal

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Tuberculosis Verrucosa Cutis (TBVC), a verrucous form of cutaneous tuberculosis, occurs from inoculation of tubercle bacilli into the skin of a previously sensitized patient with moderate to high degree of immunity. This disease is now rare in western countries and in India; the incidence of cutaneous tuberculosis has fallen from 2% to 0.15%. However two recent studies from the Indian subcontinent have reported the prevalence of cutaneous tuebrculosis as 0.7% (Varshney et al) and 0.26% (Patra et al) This case is reported to demonstrate the indolent and extensive nature of tuberculosis verrucosa cutis in an immunocompetent individual and to highlight the importance of histopathology and empirical antitubercular therapy as an adjunct diagnostic tool.

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“…Therefore, although the mechanism of pathogenesis remains uncertain, the most plausible explanation of our patient's case would be exogenous inoculation. Although the habitat for mycobacteria in this case is unusual, it is not without precedent because cases of cutaneous TB have been described in individuals from merely walking barefoot with minimal trauma [ 10 – 12 ] in endemic countries. A specific case was published in 2005 in which a 13-year-old boy from the Colombian Amazon was diagnosed with cutaneous TB by PCR and culture.…”

Section: Diagnosismentioning

confidence: 99%