Multilocular Cystic Renal Cell Carcinoma: A Rare Entity with Review of Literature

Multilocular cystic renal cell carcinoma (MCRCC) is a rare presentation of renal cell carcinoma. Most patients are asymptomatic and frequently MCRCCs are detected incidentally. MCRCCs have good prognosis because of their low malignant potential. We report a case of a 39-year-old woman who presented with mild right flank pain and normal laboratory data. On imaging examinations, a Bosniak III cystic lesion was detected in the lower third of the right kidney. She underwent right partial nephrectomy and histopathology showed a multilocular cystic renal cell carcinoma Fuhrman grade 1. In this article, we also present a review of the literature on MCRCC, highlight the correlation of the pathological and imaging characteristics of these low aggressive renal lesions, and underscore the importance of their recognition to prevent unnecessary radical surgery.

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“…The cysts are filled with gelatinous (serous or proteinaceous) and haemorrhagic fluid and no expansible solid nodules are seen 2 6 7…”

Section: Discussionmentioning

confidence: 99%

Unusual renal tumour: multilocular cystic renal cell carcinoma

Palmeiro¹,

Niza²,

Loureiro³

et al. 2016

BMJ Case Reports

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“…in 2010 have reported the first case of MCRCC metastasizing to one out of seven intra-aortocaval lymph nodes. [10]…”

Section: Discussionmentioning

confidence: 99%

Multilocular cystic renal cell carcinoma in a 23 year old female

et al. 2016

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Multilocular cystic renal cell carcinoma (MCRCC) has been identified as a separate subtype of renal cell carcinoma (RCC) in the 2004 World Health Organization classification of adult renal tumors. MCRCC represents a rare variant of clear cell RCC. The common age group for this tumor is between 40 and 60 years. In our case, MCRCC occurred at the age of 23 years in a female patient. We report this case because of its rarity in this age group, sex, good prognosis, and also to avoid a misdiagnosis as conventional clear cell RCC. However, before making a diagnosis of MCRCC, it has to be differentiated from tubulocystic carcinoma, cystic nephroma, cystic clear cell carcinoma, and clear cell papillary RCC.

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“…There may be some limited yellowish solid present, without evidence of expansile nodules of clear cells within the septa or tumor necrosis. 19…”

Section: Pathologymentioning

confidence: 99%