The globalisation trend of multicultural education has become a challenge that all countries in the world, especially multi-ethnic countries, must face directly. In order to improve the level of multicultural cognition in ethnic areas, this paper takes pre-school children as the research object, designs a multicultural education strategy based on multimedia technology, and uses the sample t-test in mathematical statistics to verify the promotion effect of the strategy on pre-school children’s multicultural cognition. The experimental group adopts the strategy described in this paper, while the control group uses conventional teaching methods. The two groups of experimental subjects are identical. Before and after the experiment, the experimental group had highly significant differences (p<0.01) in five dimensions: cultural diversity awareness, basic cultural knowledge, intercultural communication skills, cultural respect and tolerance, and cultural curiosity and desire to explore. The control group, on the other hand, only had significant differences in three dimensions: awareness of cultural diversity, cultural respect and tolerance, and cultural curiosity and desire to explore (P values of 0.032, 0.0.47, and 0.037, respectively). There are significant differences between the experimental group and the control group in all dimensions of multicultural cognition after the experiment (P<0.05). The multicultural cognition promotion strategy for preschool children in ethnic areas based on multimedia technology designed in this paper is superior to conventional teaching methods and has important reference value for multicultural cognition education in ethnic areas.