2017
DOI: 10.1098/rsta.2017.0261
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Multimodal nanoparticle imaging agents: design and applications

Abstract: Molecular imaging, where the location of molecules or nanoscale constructs can be tracked in the body to report on disease or biochemical processes, is rapidly expanding to include combined modality or multimodal imaging. No single imaging technique can offer the optimum combination of properties (e.g. resolution, sensitivity, cost, availability). The rapid technological advances in hardware to scan patients, and software to process and fuse images, are pushing the boundaries of novel medical imaging approache… Show more

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Cited by 64 publications
(54 citation statements)
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“…[62] As an emerging imaging modality with high sensitivity and depth imaging, PA imaging has been broadly proposed in cancer diagnosis and therapy. [62] As an emerging imaging modality with high sensitivity and depth imaging, PA imaging has been broadly proposed in cancer diagnosis and therapy.…”
Section: In Vitro and In Vivo Ct/pa Imagingmentioning
confidence: 99%
“…[62] As an emerging imaging modality with high sensitivity and depth imaging, PA imaging has been broadly proposed in cancer diagnosis and therapy. [62] As an emerging imaging modality with high sensitivity and depth imaging, PA imaging has been broadly proposed in cancer diagnosis and therapy.…”
Section: In Vitro and In Vivo Ct/pa Imagingmentioning
confidence: 99%
“…Multimodal imaging [6], [21]- [25] is a relatively new technique able to provide more accurate diagnosis thanks to the combination of the different imaging techniques strengths meanwhile excluding their weaknesses. It is then possible to associate a poor spatial resolution technique such as SPECT or OI with a high spatial resolution but less sensitive one like MRI or CT scan.…”
Section: Article Body Templatementioning
confidence: 99%
“…Multimodal imaging is attractivet oa chievet his specific goal by combining different imagingm odalities to obtainc omplementary information at the anatomical, functional and molecular levels. [1][2][3][4][5] The key requirementi st he availability of common probes able to operate in different imaging modalities. Among numerous imaging modalities, X-ray computedt omography( XCT) is an ideal anatomical imaging technique that allowst he detailedv isualization of organs and their contents.…”
mentioning
confidence: 99%