The safety of autonomous driving has been a constant concern, with autonomous driving becoming a research focus in the world today. This study collects the literature in the field of autonomous driving in the Web of Science core data collection from 2005 to 2020. The research status, hot research topics, and the development trend of autonomous driving are reviewed based on CiteSpace from the aspects of number of articles, national collaboration, institutions, scholars, research areas, literature co-citation, keywords, and trends. The results show that the quantitative development of autonomous driving literature has experienced three stages. The research of the United States, China, and Germany is leading in this field. The development of autonomous driving will be in the stage of man-machine driving for a long time. In this study, the progress and trend of visualization in the field of autonomous driving are given, and the future research direction is forecasted, which provides a theoretical basis for the development of autonomous driving. Furthermore, it has reference significance for relevant researchers to understand the research hotspots and future trends in this field.