“…Moreover, MINAT is sometimes associated with either mild or severe combined immunodeficiency (SCID, MIM: 601457); this combination is invariably lethal (Ali et al, 2011;Shorter et al, 2006). Although the nonhereditary form is thought to derive from vascular disruption, there have been reports of non-hereditary cases, suggesting a hereditary form of MINAT is a consequence of a malformative process of the gastrointestinal tract rather than a vascular anomaly (Baglaj et al, 2008;Puri and Fujimoto, 1988). Mutation in the tetratricopeptide repeat domaine7A (TTC7A MIM: 243150) has been shown to cause the hereditary form of MINAT (Bigorgne et al, 2014;Chen et al, 2013;Samuels et al, 2013).…”