Multiple Basal‐Cell Carcinoma of the Vulva

Basal cell carcinoma of the vulva

“…These findings corroborate previous studies that demonstrated that the tumor size ranged between 0.2 and 10 cm, and most BCCs occurred on the labia majora and less commonly on the labia minora, urethral meatus, prepuce, and clitoris [2,4,6,7,10,12,13].…”

“…This incidence is higher than the expected 2-3% reported in most previous studies [1,[3][4][5][6][8][9][10]12,13]. Nevertheless, some studies have shown that the relative frequency ranges from 0.8 to 14.7% [2,7,11].…”

“…Treatment of local recurrence consists of wide local reexcision, including a generous amount of lateral margins and underlying subcutaneous tissue [6]. Like others [2,4,6,7,12,13], we have observed that the age range of patients with vulvar BCC extended from the sixth to the ninth decade of life. The mean age of the patients in this study (70.5 years) agrees with previous studies that demonstrated that the mean age of patients with vulvar BCC ranged from 65 to 76 years [1,2,7,10,13].…”

“…Although Jews of Asian-African origin (Sephardic) make up about 60% of the Jewish population in the south of Israel, we have noticed more Jewish women of European-American origin (Ashkenazi) (6/8) than those of Asian-African origin (Sephardic) (2/8) affected by vulvar BCC. Studies from the USA have shown that vulvar BCC is more prevalent in Caucasian women than in Black women [2,4,10,11].…”

“…Vulvar BCC shares many clinical features with vulvar squamous cell carcinoma [4,7,10]: (1) mean age at diagnosis is approximately 70 years; (2) there is a predilection for Caucasians; (3) prevailing presenting symptoms are lump, ulcer, itching, and bleeding; (4) very often, there is a delay in diagnosis; (5) most tumors are located on the labia majora.…”