Multiple management strategies to prolong gestational period after radical trachelectomy

Ito, Masami; Yoneda, Satoshi; Shiozaki, Arihiro; Fukuta, Kaori; Yoneda, Noriko; Saito, Shigeru

doi:10.1002/ccr3.2400

Cited by 3 publications

(3 citation statements)

References 28 publications

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“…We as well as Speiser et al administered Metronidazole vaginal tablets for the treatment of BV during pregnancy [19]. Ito et al reported the usefulness of oral probiotics to reduce the occurrence of BV and the following pPROM for a patient after RT [20].…”

Section: Discussionmentioning

confidence: 92%

Pregnancies after vaginal radical trachelectomy (RT) in patients with early invasive uterine cervical cancer: results from a single institute

Shinkai

Ishioka

Mariya

et al. 2020

BMC Pregnancy Childbirth

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Background: Radical tracheletomy (RT) with pelvic lymphadenectomy has become an option for young patients with early invasive uterine cervical cancer who desire to maintain their fertility. However, this operative method entails a high risk for the following pregnancy due to its radicality. Methods: We have performed vaginal RT for 71 patients and have experienced 28 pregnancies in 21 patients. They were followed up carefully according to the follow-up methods we reported previously. Their pregnancy courses and prognoses after the pregnancy were retrospectively reviewed. Results: All the vaginal RTs were performed safely without serious complications, including 6 patients who underwent the operation during pregnancy. The median time to be pregnant after RT was 29.5 months. 13 patients (46%) became pregnant without artificial insemination by husband or assisted reproductive technology. Cesarean section was performed for all of them. The median time of pregnancy was 34 weeks, and emergent cesarean section was performed for 7 pregnancies (25%). The median birth weight was 2156 g. Four patients had trouble with cervical cerclage, and they suffered from sudden premature preterm rupture of the membrane (pPROM) during the second trimester of pregnancy. We underwent transabdominal cerclage (TAC) for all of them and careful management for the prevention of uterine infection was performed. One patient had a recurrence of cancer during pregnancy. Conclusions: Both the obstetrical prognosis and oncological prognosis after vaginal RT have become favorable for pregnant patients after vaginal RT.

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Section: Discussionmentioning

confidence: 92%

Pregnancies after vaginal radical trachelectomy (RT) in patients with early invasive uterine cervical cancer: results from a single institute

Shinkai

Ishioka

Mariya

et al. 2020

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

show abstract

“…Ito et al reported dichorionicdiamniotic twins after RT with multiple abnormal bleedings during pregnancy. They controlled abnormal bleeding by compression using dry gauze [50]. In our experience, hemostasis is often achieved by compression; however, in one case where hemostasis was difficult to achieve, we used an argon laser to stop the bleeding.…”

Section: Varices At the Site Of Uterovaginal Anastomosismentioning

confidence: 98%

“…Among the pregnant women after RT, there are reports of ten women pregnant with twins published previously (Table 1) [10,40,50,[57][58][59][60][61][62]. Since perinatal outcomes were not reported in detail, there was a dearth of information on managing a twin pregnancy in women after RT.…”

Section: Twin Pregnancymentioning

confidence: 99%