Multiple Papules on the Leg

Straka, Bonnie F.; Wilson, Barbara B.

doi:10.1001/archderm.1991.01680100117017

Cited by 8 publications

(4 citation statements)

References 6 publications

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“…Pain can be spontaneous or can occur after exposure to cold, pressure, injury or emotional stress [1,12,13]. Our patients, however, reported little pain.…”

Section: Discussionmentioning

confidence: 74%

Familial Multiple Cutaneous Leiomyomas

Fernández‐Pugnaire

Delgado-Florencio

1995

Dermatology

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Background: Leiomyomas are rare, benign tumors that originate from the arrector muscle of hair follicles (cutaneous leiomyoma, piloleiomyoma), the tunica dartos of the scrotum and the mammillary muscle of the nipple (genital leiomyoma), and the smooth muscle of blood vessels (angioleiomyoma). Observations: We describe 6 members of a single family with mostly painful papulonodular cutaneous lesions on the limbs, trunk and face. Histological examination of sections stained with hematoxylin-eosin and Masson trichromic stain confirmed the diagnosis of leiomyoma. All affected women had also uterine myoma. Conclusion: Our observations support the concept that this entity is an autosomally inherited disorder.

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“…Pain can be spontaneous or can occur after exposure to cold, pressure, injury or emotional stress [1,12,13]. Our patients, however, reported little pain.…”

Section: Discussionmentioning

confidence: 74%

Familial Multiple Cutaneous Leiomyomas

Fernández‐Pugnaire

Delgado-Florencio

1995

Dermatology

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“…Pain can be spontaneous or occur on exposure to cold, pressure, injury or emotional stress. 5,6,7 Our case is a presentation in a 36 year old male with family history of similar lesions in his brother. Our patient had visited the OPD in view of cosmetic concern, and pain.…”

Section: Discussionmentioning

confidence: 84%

Familial leiomyoma: a case report

Gutha¹,

Sampath²

2021

Int J Res Dermatol

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<p class="abstract">Cutaneous leiomyomas are benign tumors that can be exquisitely painful. Comprise three distinct types such as piloleimyoma, angioleiomyoma, and genital leiomyoma. Piloleiomyomas, derived from arrector pili muscle, are solitary or multiple firm papulonodules located mostly on the extremities and trunk; genital leiomyomas, derived from dartoic, vulvar, or mammary smooth muscle, are solitary or papulonodules located on the scrotum, vulva, or nipple; and angioleiomyomas, include solid, cavernous, or venous subtypes, are derived from the tunica media of small arteries and veins and typically present on the extremities. Excisional biopsy is required for diagnosing all cutaneous leiomyomas Histology shows interlacing fibers of spindle cells with moderate amounts of eosinophilic cytoplasm and a blunt-ended, elongated nucleus with perinuclear halos. Surgical excision is curative for cutaneous leiomyomas, with other management options including medical or destructive therapy. A 36-year-old male patient presented with a 13 years history of painful, multiple lesions over the back. Based on the histopathological examination, imaging, and past medical records, a diagnosis of familial leiomyoma was made. His brother had similar disease. The patient was started on tab gabapentin 300mg at night. Patient advised for carbon dioxide laser excision. The present case report has been reported for its interesting clinical presentations and rarity.</p>

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“…Multiple piloleiomyoma, most common type of cutaneous leiomyoma, are small, firm, red or brown intradermal nodules arranged in a group or linear pattern, primarily affecting the trunk and extremities but may occur on the face and neck and rarely in the mouth. 5 We extensively search for large series studies on leiomyoma cutis on internet but we found only some studies and not found any study in which more than 40 case were reported. Here we describe some studies on cutaneous leiomyoma.…”

Section: Case Reportmentioning

confidence: 99%

Cutaneous leiomyoma of scalp: a rare case report with review of literature

et al. 2015

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Skin is the largest organ of the body and many types of tumor arises from different part of skin layer. A leiomyoma is an uncommon, benign tumour of smooth muscle of skin derived from the arrector pili muscle of skin. These lesions can develop wherever smooth muscle is present, but malignant transformation probably does not occur. Cutaneous leiomyomas or piloleiomyomas appear as small (0.5-2 cm) firm skin coloured nodules. They arise from the arrector pili muscles which are responsible for making your hairs stand on end. Multiple lesions may develop, often in clusters and commonly in a segmental distribution. These nodules are benign, so are only of concern because of their appearance or their tendency to be tender if knocked. Female patients with cutaneous leiomyomas may also develop uterine leiomyomas (fibroids), and very rarely leiomyomas can be associated with renal cell carcinoma (hereditary leiomyomatosis and renal cell cancer). We report a case cutaneous leiomyoma of scalp in a 22 year old male who present with the complaints of scalp swelling.

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Multiple Papules on the Leg

Cited by 8 publications

References 6 publications

Familial Multiple Cutaneous Leiomyomas

Familial Multiple Cutaneous Leiomyomas

Familial leiomyoma: a case report

Cutaneous leiomyoma of scalp: a rare case report with review of literature

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