Multiple Primary Gastrointestinal Stromal Tumors Presenting in Jejunum and Ileum

Beltrán, Marcelo A.; Tapia, Rodrigo; Cortés, Víctor J.; Larraín, Cristóbal; Koscina, Vinka; Rioseco, María-Paz; Molina, Matías; Vera, Andrés

doi:10.1007/s12262-012-0654-x

Cited by 6 publications

(4 citation statements)

References 11 publications

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“…These were all undiagnosed primary GISTs tumours. In one patient the small intestinal GIST was associated with hepatic metastases [9] , in the other two cases small bowel GISTs were multifocal [26,29] . In all the other 19 patients there was a primary localized single GIST.…”

Section: Discussionmentioning

confidence: 90%

“…However GIST perforation seems to occur more frequently in the small bowel compared to other anatomic sites [35] . Our literature search revealed 21 cases of acute abdomen with diffuse or localized peritonitis caused by spontaneous perforation of small intestine GISTs ( Table 1 ) [9–29] . Two more cases are reported in the case-series of Mansour and Coll [8] .…”

Section: Discussionmentioning

confidence: 99%

“…Few GISTs manifest as abdominal emergencies, such as GI haemorrhage, intestinal obstruction, or tumour perforation [7,8] . Although acute abdomen due to GIST perforation into the peritoneal cavity is rare, a few cases of peritonitis caused by perforation of small-intestinal GISTs have been reported in the literature [8–29] . Together with a review of the published cases, here we report a case of an elderly patient with acute abdomen due to spontaneous perforation of a GIST located in the jejunum.…”

Section: Introductionmentioning

confidence: 99%

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Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumour of the small intestine: A case report and a literature review

Alessiani

Gianola²,

Rossi

et al. 2015

International Journal of Surgery Case Reports

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HighlightsEmergency presentation of a GIST is not uncommon and one of its manifestations is acute abdome.The cases described in the literature are the tip of the iceberg and spontaneous rupture or perforation of GISTs are a far more frequent first presentation of this rare tumour.The jejunum was the more common location of perforation compared to the ileum.Emergency surgery is mandatory and should achieve radical resection.

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Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumour of the small intestine: A case report and a literature review

Alessiani

Gianola²,

Rossi

et al. 2015

International Journal of Surgery Case Reports

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“…CT scan typically demonstrates GISTs as a heterogenous occupied lesion with high vascularity [8]. The large tumor may have a central necrotic area and intratumoral hemorrhage.…”

Section: Discussionmentioning

confidence: 99%

A giant jejunal gastrointestinal stromal tumor misconceived as pancreatic cystic neoplasm: A case report

Wongta

Tangsirapat

Ayudhya

et al. 2019

International Journal of Surgery Case Reports

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Perforated Gastrointestinal Stromal Tumor of the Meckel’s Diverticulum: a Case Report and Review of Literature

2016

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Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the GI tract, they have a wide spectrum of clinical manifestations, and a small proportion of them present as an acute abdomen due to obstruction, perforation, or hemoperitoneum. We present a case of a perforated GIST of the Meckel's diverticulum and review the current literature on perforated GISTs. We ran a search on Pubmed and Google Scholar with the following terms Bperforated GIST,^Bperforated Meckel's diverticulum,B GIST with peritonitis,^and BGIST in Meckel's diverticulum.^After selecting the relevant articles, we tabulated our results and analyzed the data. Out of the 45 cases, 32 (71.1 %) were male and 13 (28.8 %) were female. Out of the 45 reported cases, 41 (91.1 %) were from the small intestine, 2 (4.44 %) cases from the stomach, and 2 (4.44 %) from the small bowel. In 15 (33.33 %) cases, the site of perforation was the Meckel's diverticulum (MD). Forty-year-old male, presented with features of peritonitis localized to the right iliac fossa, was diagnosed as acute appendicitis and subjected to a diagnostic laparoscopy. Intraoperatively, a perforated Meckel's diverticulum was found, which on histopathological examination contained a low-grade GIST. Our literature search revealed that in reported cases of perforated GISTs, there is a slight male preponderance. Small bowel appears to be the most common site for a perforated GIST, and a significant proportion (30.23 %) arise from the Meckel's diverticulum. And most importantly, the commonest tumor to cause perforation of a Meckel's diverticulum is a GIST.

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Multiple Primary Gastrointestinal Stromal Tumors Presenting in Jejunum and Ileum

Cited by 6 publications

References 11 publications

Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumour of the small intestine: A case report and a literature review

Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumour of the small intestine: A case report and a literature review

A giant jejunal gastrointestinal stromal tumor misconceived as pancreatic cystic neoplasm: A case report

Perforated Gastrointestinal Stromal Tumor of the Meckel’s Diverticulum: a Case Report and Review of Literature

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