Multiple sclerosing hemangioma of the right lung in a 23‑year‑old female patient: A case report and review of the literature

A Case of Multiple Sclerosing Pneumocytomas With Calcifications

“…10 According to CT and pathologic findings, it was suggested that the case of our patient is extremely rare, probably < 2% of reported PSP cases. 10,11 Compared with CT and pathologic findings, FDG-PET/ CT, T2-weighted image, and unenhanced, and post-CE-Quick 3D in this case showed low FDG uptakes and excellent enhancement of nodules and micronodules. These findings were common in benign tumors and considered compatible with previous reports.…”

“…Compared with conventional dynamic CE-CT or MR imaging and CE-MR imaging, temporal resolution of dynamic CE perfusion MR imaging has been reported to be < 2 seconds and can precisely assess blood supply from pulmonary and systemic circulations. 11,13,14 Therefore, our report initially showed that PSP had a relatively lower blood supply from systemic circulation than lung cancer and gradually pooled contrast media within lesions similar to other hemangiomas, although other CT and MR results showed enhancement patterns at ≥ 20 seconds or 3 minutes after contrast media injection. 9 In conclusion, we described the radiopathologic findings in a patient with PSPs.…”

“…However, PSP is currently considered a type of benign epithelial tumor according to primitive airway epithelial origin based on immunostaining tests. [2][3][4][5][6][7][8][9][10][11] PSP is often asymptomatic and has a better prognosis than malignant lung tumors, although recurrence may occur after resection in some patients. [2][3][4][5][6][7][8][9][10][11] PSPs are composed of 4 major histologic patterns described as hemangiomatous, papillary, sclerotic, and solid that vary in proportion.…”

“…[2][3][4][5][6][7][8][9][10][11] PSP is often asymptomatic and has a better prognosis than malignant lung tumors, although recurrence may occur after resection in some patients. [2][3][4][5][6][7][8][9][10][11] PSPs are composed of 4 major histologic patterns described as hemangiomatous, papillary, sclerotic, and solid that vary in proportion. [3][4][5][6][7][8][9][10] In addition, PSP has been suggested as having pushed out vessels, internal calcification, surrounding frosted shadows, air gap, and pseudomembranes on pathologic examinations.…”

“…[3][4][5][6][7][8][9][10] In general, PSPs shown on CR or CT findings have usually been reported as a single, spherical, well-demarcated indurated nodule or mass. [3][4][5][6][7][8][9][10][11] Shin and colleagues reviewed 76 cases and reported that 70 of 76 patients (92.1%) had a single lesion, 4 patients (5.3%) had 2 lesions, and 2 patients (2.6%) had 3 or more lesions. Of the patients presenting with 3 or more lesions, 1 patient (1.3%) presented with the largest nodule with many daughter nodules, and another patient (1.3%) had multiple lesions with surrounding GGOs.…”