Multiresidue method for the simultaneous determination of 16 acaricides by modified quick, easy, cheap, effective, rugged, and safe extraction andultra-high performance liquid chromatography coupled with tandem mass spectrometry in citrus

Abstract

An ultra-high performance liquid chromatography coupled with tandem mass spectrometry analytical method was developed for simultaneously determining 16 acaricides in citrus based on an optimized quick, easy, cheap, effective, rugged, safe strategy. Good linearities of the standard curve of 5-1000 μg/kg was obtained with regression coefficients higher than 0.9967. Recoveries for all compounds ranged from 72 to 111% with relative standard deviations lower than 14.4% at spiked levels of 5, 50, and 500 μg/kg. Low limits of detection and quantification were readily achieved ranging from 0.05 to 2.7 and 0.10 to 4.3 μg/kg, respectively. Matrix effects were also evaluated for 16 targets with most compounds achieved signal enhancement. Citrus peel gave the highest extent matrix effects, followed by whole citrus and pulp. Finally, this method was successfully applied to detect acaricides residues in real citrus samples. The results showed that pyridaben and quinalphos were the two most frequent and high-concentration compounds with concentrations exceeding the maximum residue limits in five samples, suggesting that the use of these acaricides should be regulated in China in the future.

Trace Analysis of Fenbutatin Oxide in Soil and Plant- and Animal-Derived Foods Using Modified QuEChERS Coupled with HPLC-MS/MS

“…Related studies reported that the use of QuEChERS coupled with the HPLC-MS/MS method for the determination of multiresidues including fenbutatin oxide in plant-derived foods (citrus, pepper) achieved good results. 12 , 13 However, our method can be applied not only to the determination of fenbutatin oxide in plant-derived foods but also in animal-derived foods that are rich in fat, protein, and other lipophilic compounds.…”

“… 8 − 11 To the best of our knowledge, there are only two existing reports that QuEChERS coupled with the HPLC-MS/MS method was used to determine multiresidues including fenbutatin oxide in plant samples, i.e., citrus and peppers. 12 , 13 However, no report is available on the determination of fenbutatin oxide residues in animal-derived foods. The obstacle may be due to the fact that they are rich in fat, protein, and other lipophilic compounds, which are easily coextracted with the target analytes.…”

Development and validation of a multiresidue method for the simultaneous determination of organophosphorus insecticides and their toxic metabolites in sugarcane juice and refined sugar by gas chromatography with flame photometric detection

“…After the widespread acceptance and application of the QuEChERS method , acetonitrile has become largely used to extract pesticide residues from agricultural and environmental matrices . Acetonitrile was shown to be the most advantageous solvent for extraction of pesticide residues from food samples and ethyl acetate was reported to be the second best .…”

Rapid screening of amitraz and its metabolite residues in honey using a quick, easy, cheap, effective, rugged, and safe extraction method coupled with UHPLC and Q Exactive

“…N , N ‐Bis(2,4‐Dimethyliminomethyl) methylamine is a chemical called amitraz and a common organic nitrogen insecticide and acaricide mainly used to kill insects, cotton bollworms, aphids, and other pests on crops, such as vegetables, tea, and cotton [1,2]. Amitraz is less toxic to bees than other insecticides and widely used for controlling parasites in the hive to effectively prevent bee diseases caused by the Varroa destructor [3,4].…”