Multiscale Nanoparticle Assembly: From Particulate Precise Manufacturing to Colloidal Processing

Niederberger, Markus

doi:10.1002/adfm.201703647

Cited by 68 publications

(57 citation statements)

References 145 publications

(179 reference statements)

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“…They can be used as new carriers for photoactive molecules and improving the photosensitizers' biocompatibility. Moreover, the self-targeting nanomaterial enables sufficient photosensitizer enrichment in the tumor tissue, improving tumor therapeutic effects, and reducing the photosensitizer's adverse effects [66]. Recently, gold nanomaterials, carbon-based nanomaterials, and silica nanomaterials are the major substances in photodynamic therapy.…”

Section: Magnetic Nanomaterials Applications In Photodynamicmentioning

confidence: 99%

The Magnetic Nanomaterial Biofunctions in Cancer Diagnosis and Therapy

Bian

Guo

Zhang

et al. 2021

Journal of Nanomaterials

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Magnetic nanomaterials have recently emerged, playing an increasingly essential role in life science and biomedicine fields, and they exhibited promising potentials in cancer diagnosis and therapy. Also, their use as contrast agents improved various cancer diagnostic imaging sensitivities and accuracy. Magnetic nanomaterials are also exploited as targeted drug carriers to increase the sensitivity and reduce the side effects of chemotherapeutic drugs. Herein, we reviewed the preparation, characterization, and surface modification of various magnetic nanomaterials and their cancer diagnosis and therapy applications.

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Section: Magnetic Nanomaterials Applications In Photodynamicmentioning

confidence: 99%

The Magnetic Nanomaterial Biofunctions in Cancer Diagnosis and Therapy

Bian

Guo

Zhang

et al. 2021

Journal of Nanomaterials

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“…通过范德瓦尔斯作用、静电作用、熵驱动、氢键、聚合物模板、外场控制、表面配体分子结合等组装方法, 可以在多尺度上制备多种形貌的纳米颗粒组装结构. 由于组装结构中颗粒间相互作用不同, 纳米颗粒组装结构可以展现出多种新的集体性质和效应 [57,58] . 在各种纳组装方法中, 利用外加磁场控制的组装无需添加化学试剂, 操作灵活方便, 可在多尺度上形成多种形貌的组装结构, 尤其适合生物医药磁性纳米材料的组装.…”

Section: 研究表明通过调节颗粒的多级有序自组装可unclassified

Research and development of medical magnetic nanomaterials

Sun¹,

Yang²,

Ma³

et al. 2018

Chin. Sci. Bull.

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Medical magnetic nanomaterials refer to magnetic nanomaterials owning specific biological effects and therapeutic functions which are promising in clinical medicine. A good case in this point is the iron-based magnetic nanomaterials. As the only inorganic nanomaterials approved by FDA for clinical use, iron oxide nanoparticles play a vital role in fundamental research and clinical application of nanomedicine. This feature article mainly focused on the state-of-art of iron oxide nanoparticles on the basis of our own works. The following sections were included in this feature article: Preparation and magnetic property, biological effects, assembly and future development, which was intended to clarify the particularity, importance and complexity of magnetic nanomaterials applied in clinical medicine. Although thermal decomposition method can get iron oxide nanocrystals with better morphology, coprecipitation method is more suitable for the use in clinic. This issue will be emphasized. Superparamagnetism is a prominent advantage of magnetic nanomaterials for medical applications, which is closely related to their size and morphology. The biological effects of iron oxide nanoparticles are versatile and can be regulated by chemical composition, morphology and surface modification. In recent years, some new biological effects of iron oxide nanoparticles still have been found, such as the enzymatic effect. Another outstanding property of magnetic nanomaterials is that the collective property can be regulated by control of assembled structures and interactions between the nanoparticles without changing the property of monomers. Here, the magnetic field-controlled assembly of magnetic nanoparticles and the property regulation will be discussed in detail. In the future, we should firstly further investigate the synthesis of medical magnetic nanomaterials of high performance and expand the clinical applicability. Certainly, the new clinical nanodrugs should be developed. Then, the biological effects of magnetic nanomaterials in the presence of magnetic field should be explored deeply, from which we may discover some new paradigms for the clinic. Finally, the novel characterization techniques and strategies for diagnosis and treatment should be developed. We believe the magnetic nanomaterials will make the society more glorious. medical magnetic nanomaterials, biological effects, magnetic field, theranostics

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“…Along with film-substrate stability, increasing film thickness can improve a material's performance in microwave applications, energy storage capabilities, and optical and sensing properties (Rao et al, 2016;Verma et al, 2018;Cao et al, 2018;Mahender et al, 2019). There are a number of nanoparticle deposition techniques that can be used to fabricate nanoparticle films, such as drop-casting, spin-coating, dipcoating, spray-coating, aerosol deposition, electrophoretic deposition, and Langmuir-Blodgett deposition, to name several (Niederberger, 2017). One of the aforementioned methods that has received increasing attention for depositing nanoparticle films with controllable thickness and relative ease is electrophoretic deposition (EPD) (Amrollahi et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Chelating Agent Functionalized Substrates for the Formation of Thick Films via Electrophoretic Deposition

et al. 2021

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Incorporating nanoparticles into devices for a wide range of applications often requires the formation of thick films, which is particularly necessary for improving magnetic power storage, microwave properties, and sensor performance. One approach to assembling nanoparticles into films is the use of electrophoretic deposition (EPD). This work seeks to develop methods to increase film thickness and stability in EPD by increasing film-substrate interactions via functionalizing conductive substrates with various chelating agents. Here, we deposited iron oxide nanoparticles onto conductive substrates functionalized with three chelating agents with different functional moieties and differing chelating strengths. We show that increasing chelating strength can increase film-substrate interactions, resulting in thicker films when compared to traditional EPD. Results will also be presented on how the chelating strength relates to film formation as a function of deposition conditions. Yield for EPD is influenced by deposition conditions including applied electric field, particle concentration, and deposition time. This work shows that the functionalization of substrates with chelating agents that coordinate strongly with nanoparticles (phosphonic acid and dopamine) overcome parameters that traditionally hinder the deposition of thicker and more stable films, such as applied electric field and high particle concentration. We show that functionalizing substrates with chelating agents is a promising method to fabricate thick, stable films of nanoparticles deposited via EPD over a larger processing space by increasing film-substrate interactions.

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Multiscale Nanoparticle Assembly: From Particulate Precise Manufacturing to Colloidal Processing

Cited by 68 publications

References 145 publications

The Magnetic Nanomaterial Biofunctions in Cancer Diagnosis and Therapy

The Magnetic Nanomaterial Biofunctions in Cancer Diagnosis and Therapy

Research and development of medical magnetic nanomaterials

Chelating Agent Functionalized Substrates for the Formation of Thick Films via Electrophoretic Deposition

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