Multivesicular nuclear body with nucleolar activity in sertoli cells of bulls

Zibrín, M

doi:10.1007/bf00315123

Cited by 15 publications

(9 citation statements)

References 36 publications

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“…Similarly, Osman and Plö en (1979) suggested that the MNB might be able to communicate between the cytoplasm and the perinuclear space. As Zibrin (1972) suggested, the vesicles might play a role in the exchange of materials between the nucleus and cytoplasm. Unfortunately, more detailed evidence on the migratory activity of vesicles was not demonstrated in this study.…”

Section: Discussionmentioning

confidence: 94%

“…The open gap, not a break in the nuclear membrane, has been suggested by Terzakis (1965) as a window for the nucleolar channel system to migrate to the nucleoplasm. It has been proposed that the migratory activity of vesicles is a consequence of the communication between the peripheral nucleoplasm and the cytoplasm (Zibrin, 1972), while Terzakis (1965) indicated this communication in the human endometrium. Similarly, Osman and Plö en (1979) suggested that the MNB might be able to communicate between the cytoplasm and the perinuclear space.…”

Section: Discussionmentioning

confidence: 99%

“…Common scientific understanding dictates that the ruminant Sertoli cell differs from other species by the presence of certain peculiar structures, including the multivesicular nuclear body (MNB) (Terzakis et al, 1965;Zibrin, 1972 Kurohmaru et al, 1992), and irregularlyarranged microfilament bundles at the ectoplasmic specialization (Bielanska-Osuchowska and Sysa, 1981) and nodular processes (Curtis and Amann, 1981; Steinert, 1984). Among those structures, the present study focused on the postnatal development of the MNB in the Shiba goat Sertoli cell from an ultrastructural viewpoint.…”

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confidence: 98%

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Postnatal Development of Multivesicular Nuclear Body in the Shiba Goat Sertoli Cell: An Ultrastructural Study

Andriana

Mizukami²,

Ishii³

et al. 2004

Okajimas Folia Anat. Jpn.

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Summary: The multivesicular nuclear body (MNB) within the Sertoli cell nucleolus has been observed in the ruminant testis, but not in other mammalian species. Generally, the MNB is composed of vesicles, tubules and ribosome-like structures. This study has been conducted in order to clarify MNB formation during postnatal development. The testes were obtained from immature Shiba goats at 1, 2, 3, 4, and 5 months old, and from adults. They were fixed with 5% glutaraldehyde, postfixed with 1% OsO 4 , dehydrated in ethanol and embedded in Araldite-M. The serial cross-sections of seminiferous tubules were morphologically and morphometrically observed using light and transmission electron microscopy. In these Shiba goat testes, the MNB contained vesicles and tubules in various sizes, as well as ribosome-like structures. The volume of each Sertoli cell nucleus at each age (1, 2, 3, 4, 5 months old and adult) was about 269.3 mm 3 , 327.1 mm 3 , 361.3 mm 3 , 431.2 mm 3 , 525.0 mm 3 , and 760.4 mm 3 , respectively. The average number of vesicles per Sertoli cell nucleus was 0, 7.4, 11.1, 12.3, 15.5, and 32.7, respectively. At 1 month old, one or more nucleoli with fibrillar components were identified in the Sertoli cell nucleus. No MNB was observed. At 2 months old, a MNB first appeared, though it was underdeveloped and infrequently encountered. At this stage, a MNB, consisting of a small amount of vesicles and ribosomes, was located in the peripheral region of the nucleus. At later stages (3, 4, and 5 months old), MNBs gradually developed, increased in number, moved from the periphery to the central region of the nucleus, and associated with the nucleus to form a well-developed MNB. In the adults, the Sertoli cell nucleus displayed a welldeveloped and large-sized MNB situated in the central region.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 98%

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Postnatal Development of Multivesicular Nuclear Body in the Shiba Goat Sertoli Cell: An Ultrastructural Study

Andriana

Mizukami²,

Ishii³

et al. 2004

Okajimas Folia Anat. Jpn.

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“…Transmission electron microscope investigations in this study revealed that the Sertoli cell nucleus contained a multivesicular nuclear body (MNB), which itself contained tubules, ribosome like dense structures and a number of vesicles. The ruminant Sertoli cells differed from other species by presence of these atypical MNB structures [31][32][33][34][35][36][37]. It has been suggested that MNBs are similar to the nucleolar channel system found in the human endometrial glandular cell as they have a similar morphology [22,31,38,39].…”

Section: Discussionmentioning

confidence: 99%

“…It has been suggested that the MNB might be able to communicate between the cytoplasm and perinuclear space [40]. It has also been hypothesised that the vesicles in MNB assist in the exchange of materials between the nucleus and cytoplasm [32]. We found that the vesicles of MNBs contained a flocculent material, which was surrounded by electron dense aggregates of ribosome-like particles, these structures were often associated with the nuclear pores and cytoplasm suggesting that they may be involved in the synthesis and transport of substances vital to the differentiation of germ cells [9].…”

Section: Discussionmentioning

confidence: 99%

Morphological and Structural Investigations of Egyptian Water Buffalo (Bubalus Bubalis) Sertoli Cells

2017

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Buffaloes are essential part of the economy in many countries and provide sustainable food in addition to being working animals. Inefficiency in reproduction has become problematic in recent years due to a number of factors and although much research concentrates on the female, very little is known about the male buffalo reproductive system. To address this deficiency in the literature, testes were obtained from 20 clinically healthy water buffalo (Bubalus Bubalis) bulls aged 3 years old. Scanning electron microscopy showed that the Sertoli cells were columnar to triangle shaped with many processes. In the middle portion of the seminiferous tubules, the Sertoli cell had two types of processes with sheet like and slender cord like appearances. The sheet like processes had simple smooth margins originating from Sertoli cells, surrounding the surfaces of spermatogonia and spermatocytes. The slender cord like processes formed networks around other spermatogenic cells. Transmission electron microscopy showed that the Sertoli cells contained a large irregular shaped nucleus with deep nuclear membrane indentations, few mitochondria, aggregates of ribosomes and few rough endoplasmic reticulum which were observed within the indentations. Each nucleus contained a multivesicular nuclear body, containing vesicles, tubules and ribosome like dense structures. The work herein describes the structure and location of key reproductive cells within the water buffalo. Understanding the features of the male reproductive system is essential in order to advance studies into the reproductive decline of this species and the Bovidae family.

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Ultrastructure of the nucleus of human sertoli cells in normal and pathological testes

Bustos‐Obregón

Esponda

1974

Cell Tissue Res.

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Multivesicular nuclear body with nucleolar activity in sertoli cells of bulls

Cited by 15 publications

References 36 publications

Postnatal Development of Multivesicular Nuclear Body in the Shiba Goat Sertoli Cell: An Ultrastructural Study

Postnatal Development of Multivesicular Nuclear Body in the Shiba Goat Sertoli Cell: An Ultrastructural Study

Morphological and Structural Investigations of Egyptian Water Buffalo (Bubalus Bubalis) Sertoli Cells

Ultrastructure of the nucleus of human sertoli cells in normal and pathological testes

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