Muscle perfusion in the horse

Abstract

Summary Muscle perfusion was studied in conscious and anaesthetised horses by monitoring the clearance of a locally injected bolus of saline containing radioactive xenon (133Xe). The mean of all the measurements made from the brachiocephalicus and semimembranosus muscles in conscious subjects was 1.29 ml/min/100 g while in anaesthetised subjects it was 0.40 ml/min/100 g. The significance of these results is discussed in relation to the clinical occurrence of post anaesthetic myositis.

The relationship of muscle perfusion and metabolism with cardiovascular variables before and after detomidine injection during propofol–ketamine anaesthesia in horses

“…1998b; Raisis et al. 2000), 133 Xe clearance (Weaver & Lunn 1984) and microspheres (Manohar et al. 1987; Goetz et al.…”

Skeletal muscle blood flow in anaesthetized horses. Part II: effects of anaesthetics and vasoactive agents

“…Anaesthesia‐related decreases in skeletal muscle blood flow are readily quantified. The first study published in this area used radioactive xenon 133 clearance to compare microvascular perfusion in the pelvic limb muscles of conscious and halothane‐anaesthetized horses (Weaver et al. 1984) and demonstrated that perfusion decreased markedly during anaesthesia.…”

Skeletal muscle blood flow in anaesthetized horses. Part I: measurement techniques

“…Radioactive xenon 133 clearance was one of the first techniques used to non‐invasively record microvascular perfusion in conscious and anaesthetized horses (Weaver et al. 1984).…”

“…1984). This technique calculates microvascular blood flow from the rate of clearance of a small volume (0.2 mL) of radioactive xenon 133 injected at an intramuscular site (Weaver et al. 1984).…”