Musculoskeletal Imaging

Seidenberg, Peter H.; Howe, Allyson H.

doi:10.1016/j.mcna.2014.04.003

Cited by 2 publications

(2 citation statements)

References 19 publications

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“…Studies using plain x-rays to the exclusion of other imaging modalities were excluded. Plain radiographs are best utilized in evaluating osteoarthritis, fractures, dislocations and other bone abnormalities, and are not routinely indicated in soft tissue MSDs [ 23 – 26 ]. However, we may have missed some biomarkers that could be of interest such as calcifications, soft tissue swelling, or acromial abnormalities including variant acromial morphology and acromial spurs.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, for example, muscle oxygenation as measured through NIRS was included in this review. Because plain radiographs (x-rays) are best utilized in evaluating bone abnormalities and have poor contrast resolution, this imaging modality is not routinely indicated in soft tissue evaluation [ 23 – 26 ]. Thus, studies using only plain radiography were excluded from this review.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Systematic review of quantitative imaging biomarkers for neck and shoulder musculoskeletal disorders

Gold¹,

Hallman²,

Hellström³

et al. 2017

BMC Musculoskelet Disord

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Background: This study systematically summarizes quantitative imaging biomarker research in non-traumatic neck and shoulder musculoskeletal disorders (MSDs). There were two research questions: 1) Are there quantitative imaging biomarkers associated with the presence of neck and shoulder MSDs?, 2) Are there quantitative imaging biomarkers associated with the severity of neck and shoulder MSDs? Methods: PubMed and SCOPUS were used for the literature search. One hundred and twenty-five studies met primary inclusion criteria. Data were extracted from 49 sufficient quality studies. Results: Most of the 125 studies were cross-sectional and utilized convenience samples of patients as both cases and controls. Only half controlled for potential confounders via exclusion or in the analysis. Approximately one-third reported response rates. In sufficient quality articles, 82% demonstrated at least one statistically significant association between the MSD(s) and biomarker(s) studied. The literature synthesis suggested that neck muscle size may be decreased in neck pain, and trapezius myalgia and neck/shoulder pain may be associated with reduced vascularity in the trapezius and reduced trapezius oxygen saturation at rest and in response to upper extremity tasks. Reduced vascularity in the supraspinatus tendon may also be a feature in rotator cuff tears. Five of eight studies showed an association between a quantitative imaging marker and MSD severity. Conclusions: Although research on quantitative imaging biomarkers is still in a nascent stage, some MSD biomarkers were identified. There are limitations in the articles examined, including possible selection bias and inattention to potentially confounding factors. Recommendations for future studies are provided.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%