Musculoskeletal System

Hepatitis c virus-related arthritis: Bone scintigraphic appearances

“…Pathologic features of arthropathies have been translated into various patterns of findings on scintigraphic imaging modalities. [ 13 ] The pattern of symmetric peripheral joint involvement of RA can usually be distinguished scintigraphically from that of the rheumatoid variants (ankylosing spondylitis, psoriasis, Reiter's syndrome, etc. ), which tend to have more central skeletal involvement and asymmetric peripheral articular uptake.…”

False negative 99m Tc-hydroxymethane diphosphonate three-phase bone scintigraphy and 99m Tc-besilesomab scan in detecting tibia osteomyelitis concomitant with necrotizing fasciitis

“…In diabetic infection, the common route of bone involvement is via direct extension from adjacent overlying soft-tissue infection. [ 5 ] During the initial process, the pathogens invade the periosteum producing periosteitis. Osteitis and OM occur when the infection extends further into the cortex and marrow.…”

“…Osteitis and OM occur when the infection extends further into the cortex and marrow. [ 5 ] Hence, pericortical accumulation of tracer may indicate an early sign of bony involvement. Extensive soft-tissue involvement may trigger reactive response in the periosteum and results in periosteitis as well.…”

Single Photon Emission Computed Tomography-Computed Tomography (SPECT-CT) Use in Osteosarcoma with Lung Uptake

“…The principle uptake mechanism of the radiotracer is physicochemical adsorption. Metastatic deposits that produce vigorous osteoblastic response will appear as hot spot in bone scan, while the lesions that generate osteolytic reactions may not accumulate the bone radiopharmaceutical [2]. FDG-PET scan is less sensitive than bone scan in detecting bone metastases of osteosarcoma [3].…”