Musculoskeletal wide detector CT: Principles, techniques and applications in clinical practice and research

Teixeira, Pedro Augusto Gondim; Gervaise, A.; Louis, M.; Lecocq, S.; Raymond, A.; Aptel, S.; Blum, Alain

doi:10.1016/j.ejrad.2014.12.033

Cited by 28 publications

(15 citation statements)

References 33 publications

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“…BSI images generated by area detector CT allow bone removal (both cortical and trabecular) without affecting the visualization of contrast enhancement in a nonlytic bone background. [12][13][14] BSI imaging may be helpful for the diagnosis of bone invasion with or without erosive changes in cortical bone.…”

Section: Discussionmentioning

confidence: 99%

“…Currently, digital subtraction angiography-like bone subtraction iodine (BSI) imaging with 160-mm-wide area detector CT is used in some musculoskeletal and neurologic applications. [12][13][14] According to Gondim Teixeira et al, 12 BSI imaging with area detector CT showed high performance for the visual identification of bone marrow enhancement adjacent to lytic bone lesions. This technique reduces spatial mismatch by using volume scanning with wide area detector CT and a high-resolution deformable registration algorithm, enabling identification of contrast enhancement in the bone marrow.…”

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confidence: 99%

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Bone Subtraction Iodine Imaging Using Area Detector CT for Evaluation of Skull Base Invasion by Nasopharyngeal Carcinoma

Hiyama

Kuno

Koike

et al. 2018

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE: Conventional CT has generally lower detectability of bone marrow invasion than MR imaging due to lower tissue contrast. The purpose of this study was to compare the diagnostic performance of conventional CT alone or in combination with bone subtraction iodine imaging using area detector CT for the evaluation of skull base invasion in patients with nasopharyngeal carcinoma. MATERIALS AND METHODS: Forty-four consecutive patients who underwent contrast-enhanced CT using 320-row area detector CT and contrast-enhanced MR imaging for nasopharyngeal carcinoma staging between April 2012 and November 2017 were enrolled in this retrospective study. Bone subtraction iodine images were generated by subtracting pre-and postcontrast volume scans using a highresolution deformable registration algorithm. Two blinded observers evaluated skull base invasion at multiple sites (sphenoid body, clivus, bilateral base of the pterygoid process, and petrous bone) using conventional CT images alone or in combination with bone subtraction iodine images. Examination of MR and CT images by an experienced neuroradiologist was the reference standard for evaluating sensitivity, specificity, and area under the receiver operating characteristic curve. RESULTS: Twenty-six patients (59%) showed skull base invasion at 84 sites on the reference standard. Conventional CT plus bone subtraction iodine images showed higher sensitivity (92.9% versus 78.6%, P ϭ .02) and specificity (95.6% versus 86.1%, P ϭ .01) than conventional CT images alone for evaluating skull base invasion. The area under the receiver operating characteristic curve for conventional CT plus bone subtraction iodine (0.98) was significantly larger (P Ͻ .001) than the area under the receiver operating characteristic curve for conventional CT alone (0.90). CONCLUSIONS: Conventional CT plus bone subtraction iodine performs more closely to the accuracy of combining CT and MR imaging compared with conventional CT alone. ABBREVIATIONS: AUC ϭ area under the receiver operating characteristic curve; BSI ϭ bone subtraction iodine; CCT ϭ conventional CT; NPC ϭ nasopharyngeal carcinoma N asopharyngeal carcinoma (NPC), arising from the epithelial lining of the nasopharynx, has a propensity to invade the skull base just above the nasopharynx. Skull base invasion indicates a tumor stage of at least T3 according to the eighth edition of

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Bone Subtraction Iodine Imaging Using Area Detector CT for Evaluation of Skull Base Invasion by Nasopharyngeal Carcinoma

Hiyama

Kuno

Koike

et al. 2018

AJNR Am J Neuroradiol

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“…The utility of DECT in musculoskeletal imaging has been reported [ 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 ]. Although there are various applications of DECT, the detection of bone marrow oedema and bone contusion has recently been reported in the context of water-HAP images [ 7 , 24 ].…”

Section: Discussionmentioning

confidence: 99%

Improved Diagnostic Accuracy of Bone Metastasis Detection by Water-HAP Associated to Non-Contrast CT

et al. 2020

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We examined whether water-hydroxyapatite (HAP) images improve the diagnostic accuracy of bone metastasis compared with non-contrast CT alone. We retrospectively evaluated dual-energy computed tomography (DECT) images of 83 cancer patients (bone metastasis, 31; without bone metastasis, 52) from May 2018 to June 2019. Initially, two evaluators examined for bone metastasis on conventional CT images. In the second session, both CT and CT images plus water-HAP images on DECT. The confidence of bone metastasis was scored from 1 (benign) to 5 (malignant). The sensitivity, specificity, positive predictive values, and negative predictive values for both modalities were calculated based on true positive and negative findings. The intra-observer area under curve (AUC) for detecting bone metastasis was compared by receiver operating characteristic analysis. Kappa coefficient calculated the inter-observer agreement. In conventional CT images, sensitivity, specificity, positive predictive value, and negative predictive value of raters 1 and 2 for the identification of bone metastases were 0.742 and 0.710, 0.981 and 0.981, 0.958 and 0.957, and 0.864 and 0.850, respectively. In water-HAP, they were 1.00 and 1.00, 0.981 and 1.00, 0.969 and 1.00, and 1.00 and 1.00, respectively. In CT, AUCs were 0.861 and 0.845 in each observer. On water-HAP images, AUCs were 0.990 and 1.00. Kappa coefficient was 0.964 for CT and 0.976 for water-HAP images. The combination of CT and water-HAP images significantly increased diagnostic accuracy for detecting bone metastasis. Water-HAP images on DECT may enable accurate initial staging, reduced radiation exposure, and cost.

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“…5; Additional file 1: Video 1) [20]. Dynamic CTA simultaneously yields an anatomic and a functional vascular evaluation [10,11,18]. Large detector CT scanners (e.g.…”

Section: Figmentioning

confidence: 99%

“…Recently, the clinical availability of advanced CT imaging techniques, such as dynamic CTA and superhigh-resolution (SHR)-CTA, has increased. Dynamic CTA provides a functional analysis of the hand arterial network and warrants lesion evaluation at the best vascular phase [10,11]. SHR-CTA allows a clear visualisation of the most distal arteries.…”

Section: Introductionmentioning

confidence: 99%

CT angiography and MRI of hand vascular lesions: technical considerations and spectrum of imaging findings

Blum¹,

Gillet²,

Athlani

et al. 2021

Insights Imaging

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Vascular lesions of the hand are common and are distinct from vascular lesions elsewhere because of the terminal vascular network in this region, the frequent hand exposure to trauma and microtrauma, and the superficial location of the lesions. Vascular lesions in the hand may be secondary to local pathology, a proximal source of emboli, or systemic diseases with vascular compromise. In most cases, ischaemic conditions are investigated with Doppler ultrasonography. However, computed tomography angiography (CTA) or dynamic contrast-enhanced magnetic resonance angiography (MRA) is often necessary for treatment planning. MR imaging is frequently performed with MRA to distinguish between vascular malformations, vascular tumours, and perivascular tumours. Some vascular tumours preferentially affect the hand, such as pyogenic granulomas or spindle cell haemangiomas associated with Maffucci syndrome. Glomus tumours are the most frequent perivascular tumours of the hand. The purpose of this article is to describe the state-of-the-art acquisition protocols and illustrate the different patterns of vascular lesions and perivascular tumours of the hand.

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Musculoskeletal wide detector CT: Principles, techniques and applications in clinical practice and research

Cited by 28 publications

References 33 publications

Bone Subtraction Iodine Imaging Using Area Detector CT for Evaluation of Skull Base Invasion by Nasopharyngeal Carcinoma

Bone Subtraction Iodine Imaging Using Area Detector CT for Evaluation of Skull Base Invasion by Nasopharyngeal Carcinoma

Improved Diagnostic Accuracy of Bone Metastasis Detection by Water-HAP Associated to Non-Contrast CT

CT angiography and MRI of hand vascular lesions: technical considerations and spectrum of imaging findings

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