Mushroom poisoning from Inocybe serotina: A case report from Ningxia, northwest China with exact species identification and muscarine detection

Xu, Fei; Zhang, Yizhe; Zhang, Yin-Hao; Guan, Guang-Yu; Zhang, Kaiping; Li, Hai-Jiao; Wang, Junjie

doi:10.1016/j.toxicon.2020.03.003

Cited by 19 publications

(23 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…0.00006% to 0.5%. Xu et al (2020) determined the muscarine content of I. serotina by UPLC-MS/MS, and its muscarine content was 324.0 ± 62.4 mg/kg.…”

Section: Discussionmentioning

confidence: 99%

“…The procedure of toxin extraction and detection followed Xu et al (2020) with slight modifications. A 0.05 g powdery sample of dried mushroom pileus was mixed with 2 mL of a methanol-water solution (7:3 v/v) and vortexed for 30 min at room temperature.…”

Section: Methodsmentioning

confidence: 99%

“…In China, about 21 species of Inocybe s. str. are considered poisonous ( Mao 2006 ; Bau et al 2014 ; Xu et al 2020 ). However, only three species ( I.…”

Section: Introductionmentioning

confidence: 99%

“… serotina ) of Inocybe s. str. , causing typically muscarinic poisoning incidents, could be identified as containing muscarine ( Chen et al 1987 ; Xu et al 2020 ; Li et al 2021 ). Among them, I.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Two new toxic yellow Inocybe species from China: morphological characteristics, phylogenetic analyses and toxin detection

Li¹,

Xu²,

Jiang³

et al. 2021

Self Cite

View full text Add to dashboard Cite

Some species of Inocybes. str. caused neurotoxic poisoning after consumption around the world. However, there are a large number of species in this genus that have not been studied for their toxicity or toxin content. In this study, we report two new toxic yellow Inocybes. str. species from China based on morphological characteristics, phylogenetic analyses and toxin detection. Among the two species, Inocybe squarrosolutea is reported as a newly recorded species of China. We also describe a new species, I. squarrosofulva, which is morphologically similar to I. squarrosolutea. The new species is characterized by its ochraceous squarrose pileus, distinctly annulate cortina on the stipe, nodulose basidiospores and thick-walled pleurocystidia. Muscarine in the fruitbodies was detected by UPLC–MS/MS, the content in I. squarrosolutea and I. squarrosofulva were 136.4 ± 25.4 to 1683.0 ± 313 mg/kg dry weight and 31.2 ± 5.8 to 101.8 ± 18.9 mg/kg dry weight, respectively.

show abstract

“…0.00006% to 0.5%. Xu et al (2020) determined the muscarine content of I. serotina by UPLC-MS/MS, and its muscarine content was 324.0 ± 62.4 mg/kg.…”

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…In China, about 21 species of Inocybe s. str. are considered poisonous ( Mao 2006 ; Bau et al 2014 ; Xu et al 2020 ). However, only three species ( I.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Two new toxic yellow Inocybe species from China: morphological characteristics, phylogenetic analyses and toxin detection

Li¹,

Xu²,

Jiang³

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…Methods for sample preparation and analysis through UPLC-MS / MS were followed by Xu et al (2020) with some modifications. Dried samples were ground to a fine power respectively, to 20 mg of each homogenised portion, 2 mL methanol-water solution (5:95 v/v) was added.…”

Section: Materials and Methodsmentioning

confidence: 99%

Two new Inosperma (Inocybaceae) species with unexpected muscarine contents from tropical China

Deng¹,

Kang²,

Zeng³

et al. 2021

Self Cite

View full text Add to dashboard Cite

An accurate identification of poisonous mushrooms and the confirmation of the toxins involved are both of great importance in the treatment of mushroom poisoning incidents. In recent years, cases of mushroom poisoning by Inosperma spp. have been repeatedly reported from tropical Asia. It is urgent to know the real species diversity of Inosperma in this region. In the present study, we proposed two new Inosperma species from tropical Asia, namely I. muscarium and I. hainanense. They were described based on morphology and multilocus phylogeny. Detailed descriptions, color photographs and the discussion with other closely related species of the two new taxa were provided. In addition, a comprehensive muscarine determination of these two new species using ultrahigh performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) approach has been performed. Results showed that these two species were muscarine positive, with a content of 16.03 ± 1.23 g/kg in I. muscarium and a content of 11.87 ± 3.02 g/kg in I. hainanense, much higher than the known species I. virosum. Recovery of muscarine ranged from 93.45% to 97.25%, and the average recovery is 95.56%.

show abstract

Rapid screening for 315 drugs in food and biological matrices by ultrahigh‐performance liquid chromatography quadrupole time of flight mass spectrometry and its application to a specific incident

Guo

Yang

Zhang

2022

Separation Science Plus

View full text Add to dashboard Cite

Comprehensive screening of harmful chemical drugs in food is an essential analytical tool in the investigation of food poisoning. Meanwhile, determining harmful chemical drugs in biological matrices is a supplement to support the screening results in food. In this study, we developed a screening method for 315 harmful chemical drugs in food and biological matrices based on ultrahigh-performance liquid chromatography quadrupole time of flight mass spectrometry. The food and gastric juice sample was extracted by 1.0% formic acid acetonitrile and acetonitrile, respectively, and cleaned up by a C18 sorbent. Urine and serum were directly extracted by 1.0 % formic acid acetonitrile. Then the data was acquired and screened for drugs using a self-built library. The recovery, accuracy, and limit of quantitation for methodology were investigated. The method was validated by other three laboratories in different areas in China using different mass spectrometric techniques. For screening, the coefficient of variation of the retention times was below 5%. The recoveries for the drugs in nine matrices were 70-120%.At last, the developed method was applied to a real incident, demonstrating its suitability for the sensitive and fast screening of harmful chemical drugs in food and biological samples.

show abstract

Mushroom poisoning from Inocybe serotina: A case report from Ningxia, northwest China with exact species identification and muscarine detection

Cited by 19 publications

References 6 publications

Two new toxic yellow Inocybe species from China: morphological characteristics, phylogenetic analyses and toxin detection

Two new toxic yellow Inocybe species from China: morphological characteristics, phylogenetic analyses and toxin detection

Two new Inosperma (Inocybaceae) species with unexpected muscarine contents from tropical China

Rapid screening for 315 drugs in food and biological matrices by ultrahigh‐performance liquid chromatography quadrupole time of flight mass spectrometry and its application to a specific incident

Contact Info

Product

Resources

About

Mushroom poisoning from Inocybe serotina: A case report from Ningxia, northwest China with exact species identification and muscarine detection

Cited by 19 publications

References 6 publications

Two new toxic yellow Inocybe species from China: morphological characteristics, phylogenetic analyses and toxin detection

Two new toxic yellow Inocybe species from China: morphological characteristics, phylogenetic analyses and toxin detection

﻿Two new Inosperma (Inocybaceae) species with unexpected muscarine contents from tropical China

Rapid screening for 315 drugs in food and biological matrices by ultrahigh‐performance liquid chromatography quadrupole time of flight mass spectrometry and its application to a specific incident

Contact Info

Product

Resources

About

Two new Inosperma (Inocybaceae) species with unexpected muscarine contents from tropical China