Mutagenic action of heavy ions on Escherichia coli cells

beta-galactosidase and alkaline phosphatase activities of Escherichia coli strain PQ37 carrying the fusion gene of sulA and lacZ treated with different types of ionizing radiation were examined. The induction factor (ratio of beta-galactosidase to alkaline phosphatase activity), reflecting the SOS-induction potency, increases significantly with radiation dose. Maximum effectiveness to induce SOS-response has been found for deuterium and helium ions in comparison to gamma-rays, carbon or krypton ions. Increased energy of helium ions leads to greater SOS-induction potency of radiation.

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Induction of SOS repair by ionizing radiation

Koudela

Rýznar

Kozubek

et al. 1992

Radiat Environ Biophys

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The effect of the anoxic radiosensitizing agent TAN on induction of revertants by γ-rays and helium ions in Salmonella tester strains

Basha

Krasavin

Kozubek

1992

Mutation Research/Fundamental and Molecular Mechanisms of Mutag

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Radioprotective action of glycerol and cysteamine on inactivation and mutagenesis in Salmonella tester strains after γ- and heavy ion irradiation

Basha

Krasavin

Kozubek

1992

Mutation Research/Fundamental and Molecular Mechanisms of Mutag

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Mutagenic action of heavy ions on Escherichia coli cells

Cited by 14 publications

References 14 publications

Induction of SOS repair by ionizing radiation

Induction of SOS repair by ionizing radiation

The effect of the anoxic radiosensitizing agent TAN on induction of revertants by γ-rays and helium ions in Salmonella tester strains

Radioprotective action of glycerol and cysteamine on inactivation and mutagenesis in Salmonella tester strains after γ- and heavy ion irradiation

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