Mycoplasmas and Erythema Multiforme

Pathogenesis of extrapulmonary manifestations of Mycoplasma pneumoniae infection with special reference to pneumonia

“…For simplicity's sake, this review approaches the matter from a pathogenetic point of view, so that the term SJS is arbitrarily used to represent a severe, bullous form involving both mucous and cutaneous lesions, and the term erythema multiforme is used to represent a milder, nonbullous form not involving mucous lesion. Based on this classification, SJS can be called a direct-type extrapulmonary manifestation, since M. pneumoniae was reported to have been successfully isolated from blister fluid of patients with SJS [27,28]. Considering the biological nature of M. pneumoniae, it is unlikely that M. pneumoniae directly infects and propagates on the squamous epithelium of the skin.…”

Mycoplasma pneumoniae–induced Stevens-Johnson syndrome without skin lesions: Fact or fiction?

“…Rarely, M pneumoniae has been cultured from skin bullae, suggesting that primary skin infection is possible. [1][2][3] Nevertheless, almost all cutaneous signs caused by this organism are secondary skin reaction patterns (Table I).…”

Erythema multiforme (Stevens-Johnson Syndrome) – Chart Review of 123 Hospitalized Patients

“…Herpes sim plex infection is associated with it [7][8][9] as is mycoplasma infection [10] as well as other infectious processes [11][12][13][14][15]. Drugs [16][17][18][19][20][21][22] 384 Nethercott/Choi are commonly associated.…”